| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Nuclear receptor subfamily 4 group A member 2 |
|---|
| Ligand | BDBM50577610 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2130664 (CHEMBL4840093) |
|---|
| IC50 | 4000±n/a nM |
|---|
| Citation |  Zaienne, D; Willems, S; Schierle, S; Heering, J; Merk, D Development and Profiling of Inverse Agonist Tools for the Neuroprotective Transcription Factor Nurr1. J Med Chem64:15126-15140 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Nuclear receptor subfamily 4 group A member 2 |
|---|
| Name: | Nuclear receptor subfamily 4 group A member 2 |
|---|
| Synonyms: | NOT | NR4A2 | NR4A2_HUMAN | NURR1 | TINUR |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 66603.77 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_453027 |
|---|
| Residue: | 598 |
|---|
| Sequence: | MPCVQAQYGSSPQGASPASQSYSYHSSGEYSSDFLTPEFVKFSMDLTNTEITATTSLPSF
STFMDNYSTGYDVKPPCLYQMPLSGQQSSIKVEDIQMHNYQQHSHLPPQSEEMMPHSGSV
YYKPSSPPTPTTPGFQVQHSPMWDDPGSLHNFHQNYVATTHMIEQRKTPVSRLSLFSFKQ
SPPGTPVSSCQMRFDGPLHVPMNPEPAGSHHVVDGQTFAVPNPIRKPASMGFPGLQIGHA
SQLLDTQVPSPPSRGSPSNEGLCAVCGDNAACQHYGVRTCEGCKGFFKRTVQKNAKYVCL
ANKNCPVDKRRRNRCQYCRFQKCLAVGMVKEVVRTDSLKGRRGRLPSKPKSPQEPSPPSP
PVSLISALVRAHVDSNPAMTSLDYSRFQANPDYQMSGDDTQHIQQFYDLLTGSMEIIRGW
AEKIPGFADLPKADQDLLFESAFLELFVLRLAYRSNPVEGKLIFCNGVVLHRLQCVRGFG
EWIDSIVEFSSNLQNMNIDISAFSCIAALAMVTERHGLKEPKRVEELQNKIVNCLKDHVT
FNNGGLNRPNYLSKLLGKLPELRTLCTQGLQRIFYLKLEDLVPPPAIIDKLFLDTLPF
|
|
|
|---|
| BDBM50577610 |
|---|
| n/a |
|---|
| Name | BDBM50577610 |
|---|
| Synonyms: | CHEMBL4877438 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H13NO2S |
|---|
| Mol. Mass. | 271.334 |
|---|
| SMILES | COC(=O)c1cn(C)c2ccc(cc12)-c1cccs1 |
|---|
| Structure | 
|
|---|
Search and Browse
