| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-hexosaminidase |
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| Ligand | BDBM50577843 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2131146 (CHEMBL4840661) |
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| Ki | 47±n/a nM |
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| Citation |  Kiss, M; Szabó, E; Bocska, B; Sinh, LT; Fernandes, CP; Timári, I; Hayes, JM; Somsák, L; Barna, T Nanomolar inhibition of human OGA by 2-acetamido-2-deoxy-d-glucono-1,5-lactone semicarbazone derivatives. Eur J Med Chem223:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-hexosaminidase |
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| Name: | Beta-hexosaminidase |
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| Synonyms: | HEXB |
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| Type: | PROTEIN |
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| Mol. Mass.: | 61269.39 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_120526 |
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| Residue: | 537 |
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| Sequence: | MEQRGLARLRLPGLLALLAALAARTPRVSASGDLNLWPLPVSLKTTPRLFYLSPGNFFFG
HSPTSKAGPSCAVLQEAFRRYYDYIFGFYKWHHGHNKIPSEMELQKLEVSVIMDPECDSF
PSITSDESYTLLVKGPVATLTANRVWGVLRGLETFSQLIYQDSYGTFTANESNIVDSPRF
PHRGILIDTSRHFLPVKTILKTLDAMAFNKFNVLHWHIVDDQSFPYQSISFPELSNKGSY
SLSHVYTPNDVRTVIEYARLRGIRVLPEFDSPGHTESWGKGQKDLLTPCYHAREPSGTFG
PINPILNSTYSFLSKLFKEISTVFPDEFIHLGGDEVNFNCWESNPAVLNFMMNKGFGKNF
KKLQSFYMQMVLDMISTMKKRSIVWQEVYDDEGKLLPGTVVQVWKMGDFYKELENITAAG
FPVIISAPWYLDVINYGQDWRQYYSVKPLNFAGTPEQKQLVIGGEACIWGEYVDATNLTP
RLWPRASAVGERLWSPQEVTDLDDAYRRLTRHRCRMVRRGIAAQPLFTGYCEHEGRM
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| BDBM50577843 |
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| n/a |
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| Name | BDBM50577843 |
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| Synonyms: | CHEMBL4853460 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22N4O6 |
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| Mol. Mass. | 402.4012 |
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| SMILES | CC(=O)N[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O\C1=N/NC(=O)Nc1ccc2ccccc2c1 |r| |
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| Structure | 
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