| Reaction Details |
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 | Report a problem with these data |
| Target | Sigma non-opioid intracellular receptor 1 |
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| Ligand | BDBM50145014 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_200962 (CHEMBL802050) |
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| Ki | 0.31±n/a nM |
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| Citation |  Berardi, F; Ferorelli, S; Abate, C; Colabufo, NA; Contino, M; Perrone, R; Tortorella, V 4-(tetralin-1-yl)- and 4-(naphthalen-1-yl)alkyl derivatives of 1-cyclohexylpiperazine as sigma receptor ligands with agonist sigma2 activity. J Med Chem47:2308-17 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Sigma non-opioid intracellular receptor 1 |
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| Name: | Sigma non-opioid intracellular receptor 1 |
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| Synonyms: | Aging-associated gene 8 protein | OPRS1 | SGMR1_HUMAN | SIG-1R | SIGMAR1 | SR-BP | SR31747-binding protein | SRBP | Sigma 1-type opioid receptor | Sigma opioid receptor | Sigma1R | hSigmaR1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 25124.85 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q99720 |
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| Residue: | 223 |
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| Sequence: | MQWAVGRRWAWAALLLAVAAVLTQVVWLWLGTQSFVFQREEIAQLARQYAGLDHELAFSR
LIVELRRLHPGHVLPDEELQWVFVNAGGWMGAMCLLHASLSEYVLLFGTALGSRGHSGRY
WAEISDTIISGTFHQWREGTTKSEVFYPGETVVHGPGEATAVEWGPNTWMVEYGRGVIPS
TLAFALADTVFSTQDFLTLFYTLRSYARGLRLELTTYLFGQDP
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| BDBM50145014 |
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| n/a |
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| Name | BDBM50145014 |
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| Synonyms: | 1-Cyclohexyl-4-(5-methoxy-1,2,3,4-tetrahydro-naphthalen-1-ylmethyl)-piperazine | CHEMBL75878 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H34N2O |
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| Mol. Mass. | 342.5182 |
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| SMILES | COc1cccc2C(CN3CCN(CC3)C3CCCCC3)CCCc12 |
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| Structure | 
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