| Reaction Details |
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 | Report a problem with these data |
| Target | Potassium voltage-gated channel subfamily A member 3 |
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| Ligand | BDBM50145060 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_214956 (CHEMBL821185) |
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| Kd | 70000±n/a nM |
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| Citation |  Baell, JB; Gable, RW; Harvey, AJ; Toovey, N; Herzog, T; Hänsel, W; Wulff, H Khellinone derivatives as blockers of the voltage-gated potassium channel Kv1.3: synthesis and immunosuppressive activity. J Med Chem47:2326-36 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Potassium voltage-gated channel subfamily A member 3 |
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| Name: | Potassium voltage-gated channel subfamily A member 3 |
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| Synonyms: | HGK5 | HLK3 | HPCN3 | HuKIII | KCNA3 | KCNA3_HUMAN | Potassium voltage-gated channel subfamily A member 3 | Voltage-gated potassium channel | Voltage-gated potassium channel subunit Kv1.3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 63835.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1513935 |
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| Residue: | 575 |
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| Sequence: | MDERLSLLRSPPPPSARHRAHPPQRPASSGGAHTLVNHGYAEPAAGRELPPDMTVVPGDH
LLEPEVADGGGAPPQGGCGGGGCDRYEPLPPSLPAAGEQDCCGERVVINISGLRFETQLK
TLCQFPETLLGDPKRRMRYFDPLRNEYFFDRNRPSFDAILYYYQSGGRIRRPVNVPIDIF
SEEIRFYQLGEEAMEKFREDEGFLREEERPLPRRDFQRQVWLLFEYPESSGPARGIAIVS
VLVILISIVIFCLETLPEFRDEKDYPASTSQDSFEAAGNSTSGSRAGASSFSDPFFVVET
LCIIWFSFELLVRFFACPSKATFSRNIMNLIDIVAIIPYFITLGTELAERQGNGQQAMSL
AILRVIRLVRVFRIFKLSRHSKGLQILGQTLKASMRELGLLIFFLFIGVILFSSAVYFAE
ADDPTSGFSSIPDAFWWAVVTMTTVGYGDMHPVTIGGKIVGSLCAIAGVLTIALPVPVIV
SNFNYFYHRETEGEEQSQYMHVGSCQHLSSSAEELRKARSNSTLSKSEYMVIEEGGMNHS
AFPQTPFKTGNSTATCTTNNNPNSCVNIKKIFTDV
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| BDBM50145060 |
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| n/a |
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| Name | BDBM50145060 |
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| Synonyms: | 5-[(1E)-1-[(E)-2-[1-(6-hydroxy-4,7-dimethoxy-1-benzofuran-5-yl)ethylidene]hydrazin-1-ylidene]ethyl]-4,7-dimethoxy-1-benzofuran-6-ol | CHEMBL310762 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H24N2O8 |
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| Mol. Mass. | 468.456 |
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| SMILES | COc1c(O)c(C(C)=NN=C(C)c2c(O)c(OC)c3occc3c2OC)c(OC)c2ccoc12 |w:9.8,6.6| |
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| Structure | 
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