| Reaction Details |
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 | Report a problem with these data |
| Target | Somatostatin receptor type 2 |
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| Ligand | BDBM50578115 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2132047 (CHEMBL4841562) |
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| EC50 | 0.470000±n/a nM |
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| Citation |  Ishida, A; Okabe, Y; Matsushita, T; Sekiguchi, T; Nishio, T; Komagata, T; Iwaki, M; Miyata, H; Katagi, J; Naganawa, A; Maruyama, T; Imagawa, A Design, synthesis, and biological evaluation of novel somatostatin receptor subtype-2 agonists: Optimization for potency and risk mitigation of hERG and phospholipidosis. Bioorg Med Chem49:0 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Somatostatin receptor type 2 |
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| Name: | Somatostatin receptor type 2 |
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| Synonyms: | SOMATOSTATIN SST2 | SRIF-1 | SS-2-R | SS2-R | SS2R | SSR2_HUMAN | SSTR2 | Somatostatin receptor type 2 (SSTR2) |
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| Type: | Enzyme |
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| Mol. Mass.: | 41344.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30874 |
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| Residue: | 369 |
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| Sequence: | MDMADEPLNGSHTWLSIPFDLNGSVVSTNTSNQTEPYYDLTSNAVLTFIYFVVCIIGLCG
NTLVIYVILRYAKMKTITNIYILNLAIADELFMLGLPFLAMQVALVHWPFGKAICRVVMT
VDGINQFTSIFCLTVMSIDRYLAVVHPIKSAKWRRPRTAKMITMAVWGVSLLVILPIMIY
AGLRSNQWGRSSCTINWPGESGAWYTGFIIYTFILGFLVPLTIICLCYLFIIIKVKSSGI
RVGSSKRKKSEKKVTRMVSIVVAVFIFCWLPFYIFNVSSVSMAISPTPALKGMFDFVVVL
TYANSCANPILYAFLSDNFKKSFQNVLCLVKVSGTDDGERSDSKQDKSRLNETTETQRTL
LNGDLQTSI
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| BDBM50578115 |
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| n/a |
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| Name | BDBM50578115 |
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| Synonyms: | CHEMBL4856293 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H23Cl2N5O2 |
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| Mol. Mass. | 460.356 |
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| SMILES | Cc1nc(C(=O)Nc2cncc(-c3cc(Cl)cc(Cl)c3)c2N2CCC(N)CC2)c(C)o1 |
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| Structure | 
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