| Reaction Details |
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 | Report a problem with these data |
| Target | Tyrosinase |
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| Ligand | BDBM50146418 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_213286 |
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| IC50 | 330±n/a nM |
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| Citation |  Kim, H; Choi, J; Cho, JK; Kim, SY; Lee, YS Solid-phase synthesis of kojic acid-tripeptides and their tyrosinase inhibitory activity, storage stability, and toxicity. Bioorg Med Chem Lett14:2843-6 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Tyrosinase |
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| Name: | Tyrosinase |
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| Synonyms: | LB24-AB | Monophenol monooxygenase | SK29-AB | TYR | TYRO_HUMAN | Tumor rejection antigen AB |
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| Type: | Protein |
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| Mol. Mass.: | 60388.08 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P14679 |
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| Residue: | 529 |
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| Sequence: | MLLAVLYCLLWSFQTSAGHFPRACVSSKNLMEKECCPPWSGDRSPCGQLSGRGSCQNILL
SNAPLGPQFPFTGVDDRESWPSVFYNRTCQCSGNFMGFNCGNCKFGFWGPNCTERRLLVR
RNIFDLSAPEKDKFFAYLTLAKHTISSDYVIPIGTYGQMKNGSTPMFNDINIYDLFVWMH
YYVSMDALLGGSEIWRDIDFAHEAPAFLPWHRLFLLRWEQEIQKLTGDENFTIPYWDWRD
AEKCDICTDEYMGGQHPTNPNLLSPASFFSSWQIVCSRLEEYNSHQSLCNGTPEGPLRRN
PGNHDKSRTPRLPSSADVEFCLSLTQYESGSMDKAANFSFRNTLEGFASPLTGIADASQS
SMHNALHIYMNGTMSQVQGSANDPIFLLHHAFVDSIFEQWLRRHRPLQEVYPEANAPIGH
NRESYMVPFIPLYRNGDFFISSKDLGYDYSYLQDSDPDSFQDYIKSYLEQASRIWSWLLG
AAMVGAVLTALLAGLVSLLCRHKRKQLPEEKQPLLMEKEDYHSLYQSHL
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| BDBM50146418 |
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| n/a |
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| Name | BDBM50146418 |
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| Synonyms: | (S)-2-{(S)-2-[(S)-2-(5-Hydroxy-4-oxo-4H-pyran-2-ylmethoxycarbonylamino)-1-oxo-3-phenyl-propylamino]-3-phenyl-propionylamino}-3-(4-hydroxy-phenyl)-propionic acid | CHEMBL98925 |
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| Type | Small organic molecule |
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| Emp. Form. | C34H33N3O10 |
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| Mol. Mass. | 643.6399 |
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| SMILES | OC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)OCc1cc(=O)c(O)co1 |
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| Structure | 
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