Reaction Details |
| Report a problem with these data |
Target | Gag-Pol polyprotein [489-587] |
---|
Ligand | BDBM50147197 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_158997 (CHEMBL763924) |
---|
IC50 | 3000±n/a nM |
---|
Citation | Yehia, NA; Antuch, W; Beck, B; Hess, S; Schauer-Vukasinovic, V; Almstetter, M; Furer, P; Herdtweck, E; Dömling, A Novel nonpeptidic inhibitors of HIV-1 protease obtained via a new multicomponent chemistry strategy. Bioorg Med Chem Lett14:3121-5 (2004) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
Gag-Pol polyprotein [489-587] |
---|
Name: | Gag-Pol polyprotein [489-587] |
Synonyms: | Human immunodeficiency virus type 1 protease | POL_HV1H2 | Pol polyprotein | gag-pol |
Type: | Enzyme Subunit |
Mol. Mass.: | 10781.16 |
Organism: | Human immunodeficiency virus type 1 |
Description: | P04585[489-587] |
Residue: | 99 |
Sequence: | PQVTLWQRPLVTIKIGGQLKEALLDTGADDTVLEEMSLPGRWKPKMIGGIGGFIKVRQYD
QILIEICGHKAIGTVLVGPTPVNIIGRNLLTQIGCTLNF
|
|
|
BDBM50147197 |
---|
n/a |
---|
Name | BDBM50147197 |
Synonyms: | 3-Hydroxy-5-oxo-2,4-diphenethyl-2,5-dihydro-furan-2-carboxylic acid tert-butylamide | CHEMBL104253 |
Type | Small organic molecule |
Emp. Form. | C25H29NO4 |
Mol. Mass. | 407.5021 |
SMILES | CC(C)(C)NC(=O)C1(CCc2ccccc2)OC(=O)C(CCc2ccccc2)C1=O |
Structure |
|