| Reaction Details |
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 | Report a problem with these data |
| Target | Anionic trypsin |
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| Ligand | BDBM50147492 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_213079 |
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| Ki | 294000±n/a nM |
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| Citation |  Kranjc, A; Peterlin-Masic, L; Ilas, J; Prezelj, A; Stegnar, M; Kikelj, D Novel thrombin inhibitors incorporating weakly basic heterobicyclic P1-arginine mimetics: optimization via modification of P1 and P3 moieties. Bioorg Med Chem Lett14:3251-6 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Anionic trypsin |
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| Name: | Anionic trypsin |
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| Synonyms: | Anionic trypsin | TRY2_BOVIN | Trypsin II |
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| Type: | PROTEIN |
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| Mol. Mass.: | 26281.39 |
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| Organism: | Bos taurus |
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| Description: | ChEMBL_212177 |
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| Residue: | 247 |
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| Sequence: | MHPLLILAFVGAAVAFPSDDDDKIVGGYTCAENSVPYQVSLNAGYHFCGGSLINDQWVVS
AAHCYQYHIQVRLGEYNIDVLEGGEQFIDASKIIRHPKYSSWTLDNDILLIKLSTPAVIN
ARVSTLLLPSACASAGTECLISGWGNTLSSGVNYPDLLQCLVAPLLSHADCEASYPGQIT
NNMICAGFLEGGKDSCQGDSGGPVACNGQLQGIVSWGYGCAQKGKPGVYTKVCNYVDWIQ
ETIAANS
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| BDBM50147492 |
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| n/a |
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| Name | BDBM50147492 |
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| Synonyms: | CHEMBL109345 | N-((S)-2-Amino-4,5,6,7-tetrahydro-benzothiazol-6-yl)-2-(6-methyl-2-oxo-3-phenylmethanesulfonylamino-2H-pyridin-1-yl)-acetamide |
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| Type | Small organic molecule |
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| Emp. Form. | C22H25N5O4S2 |
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| Mol. Mass. | 487.595 |
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| SMILES | Cc1ccc(NS(=O)(=O)Cc2ccccc2)c(=O)n1CC(=O)N[C@H]1CCc2nc(N)sc2C1 |
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| Structure | 
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