| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A2a |
|---|
| Ligand | BDBM50059101 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_27616 (CHEMBL639492) |
|---|
| Ki | 630±n/a nM |
|---|
| Citation |  Ferrarini, PL; Betti, L; Cavallini, T; Giannaccini, G; Lucacchini, A; Manera, C; Martinelli, A; Ortore, G; Saccomanni, G; Tuccinardi, T Study on affinity profile toward native human and bovine adenosine receptors of a series of 1,8-naphthyridine derivatives. J Med Chem47:3019-31 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A2a |
|---|
| Name: | Adenosine receptor A2a |
|---|
| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 44716.46 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P29274 |
|---|
| Residue: | 412 |
|---|
| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
|
|
|
|---|
| BDBM50059101 |
|---|
| n/a |
|---|
| Name | BDBM50059101 |
|---|
| Synonyms: | 2-(4-Fluoro-phenyl)-7-methyl-1H-[1,8]naphthyridin-4-one | 2-(4-Fluoro-phenyl)-7-methyl-[1,8]naphthyridin-4-ol | 2-(4-fluorophenyl)-7-methyl-1,8-naphthyridin-4-ol | CHEMBL313864 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H11FN2O |
|---|
| Mol. Mass. | 254.259 |
|---|
| SMILES | Cc1ccc2c(O)cc(nc2n1)-c1ccc(F)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
