| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50580832 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2149054 (CHEMBL5033452) |
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| Ki | 6.0±n/a nM |
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| Citation |  García, M; Llorente, V; Garriga, L; Christmann, U; Rodríguez-Escrich, S; Virgili, M; Fernández, B; Bordas, M; Ayet, E; Burgueño, J; Pujol, M; Dordal, A; Portillo-Salido, E; Gris, G; Vela, JM; Almansa, C Propionamide Derivatives as Dual ?-Opioid Receptor Agonists and ? J Med Chem64:10139-10154 (2021) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50580832 |
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| n/a |
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| Name | BDBM50580832 |
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| Synonyms: | CHEMBL5089000 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H33F3N4OS |
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| Mol. Mass. | 506.627 |
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| SMILES | CCC(=O)N(CC1(CCSCC1)N1CCN(Cc2ccccc2)CC1)c1cccc(n1)C(F)(F)F |
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| Structure | 
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