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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Amine oxidase [flavin-containing] A | ||
| Ligand | BDBM50148817 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_123279 (CHEMBL731800) | ||
| IC50 | 17800±n/a nM | ||
| Citation |  Velezheva, VS; Brennan, PJ; Marshakov, VY; Gusev, DV; Lisichkina, IN; Peregudov, AS; Tchernousova, LN; Smirnova, TG; Andreevskaya, SN; Medvedev, AE Novel pyridazino[4,3-b]indoles with dual inhibitory activity against Mycobacterium tuberculosis and monoamine oxidase. J Med Chem47:3455-61 (2004) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Amine oxidase [flavin-containing] A | |||
| Name: | Amine oxidase [flavin-containing] A | ||
| Synonyms: | AOFA_RAT | Amine oxidase (flavin-containing) A | Amine oxidase [flavin-containing] A | Maoa | Monoamine Oxidase Type A (MAO-A) | Monoamine oxidase | Monoamine oxidase A (MAO-A) | Monoamine oxidase A (rMAO-A) | Monoamine oxidase type A (MAOA) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 59515.21 | ||
| Organism: | Rattus norvegicus (rat) | ||
| Description: | n/a | ||
| Residue: | 526 | ||
| Sequence: |
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| BDBM50148817 | |||
| n/a | |||
| Name | BDBM50148817 | ||
| Synonyms: | 5-Benzyl-4-(2-chloro-phenyl)-5H-pyridazino[4,3-b]indol-3-ylamine | CHEMBL325620 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H17ClN4 | ||
| Mol. Mass. | 384.861 | ||
| SMILES | Nc1nnc2c3ccccc3n(Cc3ccccc3)c2c1-c1ccccc1Cl |(8.52,2.84,;6.99,2.81,;6.14,4.12,;4.61,4.04,;3.89,2.67,;2.42,2.27,;1.12,3.11,;-.25,2.41,;-.33,.9,;.96,.05,;2.33,.74,;3.77,.2,;4.17,-1.29,;3.08,-2.37,;1.61,-1.98,;.52,-3.06,;.92,-4.54,;2.4,-4.94,;3.49,-3.85,;4.73,1.37,;6.27,1.44,;7.1,.14,;6.38,-1.21,;7.19,-2.52,;8.73,-2.45,;9.45,-1.1,;8.64,.2,;9.97,.98,)| | ||
| Structure | 
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