| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Melatonin receptor type 1A |
|---|
| Ligand | BDBM50149169 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_104948 |
|---|
| Ki | 0.700000±n/a nM |
|---|
| Citation |  Sun, LQ; Chen, J; Bruce, M; Deskus, JA; Epperson, JR; Takaki, K; Johnson, G; Iben, L; Mahle, CD; Ryan, E; Xu, C Synthesis and structure-activity relationship of novel benzoxazole derivatives as melatonin receptor agonists. Bioorg Med Chem Lett14:3799-802 (2004) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Melatonin receptor type 1A |
|---|
| Name: | Melatonin receptor type 1A |
|---|
| Synonyms: | MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 39392.94 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P48039 |
|---|
| Residue: | 350 |
|---|
| Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
|
|
|
|---|
| BDBM50149169 |
|---|
| n/a |
|---|
| Name | BDBM50149169 |
|---|
| Synonyms: | CHEMBL127570 | Cyclopropanecarboxylic acid [3-(2-methyl-benzooxazol-7-yl)-propyl]-amide |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C15H18N2O2 |
|---|
| Mol. Mass. | 258.3156 |
|---|
| SMILES | Cc1nc2cccc(CCCNC(=O)C3CC3)c2o1 |
|---|
| Structure | 
|
|---|
Search and Browse
