| Reaction Details |
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 | Report a problem with these data |
| Target | Trace amine-associated receptor 1 |
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| Ligand | BDBM50359505 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2151755 (CHEMBL5036217) |
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| EC50 | 225±n/a nM |
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| Citation |  Heffernan, MLR; Herman, LW; Brown, S; Jones, PG; Shao, L; Hewitt, MC; Campbell, JE; Dedic, N; Hopkins, SC; Koblan, KS; Xie, L Ulotaront: A TAAR1 Agonist for the Treatment of Schizophrenia. ACS Med Chem Lett13:92-98 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Trace amine-associated receptor 1 |
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| Name: | Trace amine-associated receptor 1 |
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| Synonyms: | TA1 | TAAR1 | TAAR1_HUMAN | TAR1 | TRAR1 | trace amine-associated receptor 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 39107.47 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_792734 |
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| Residue: | 339 |
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| Sequence: | MMPFCHNIINISCVKNNWSNDVRASLYSLMVLIILTTLVGNLIVIVSISHFKQLHTPTNW
LIHSMATVDFLLGCLVMPYSMVRSAEHCWYFGEVFCKIHTSTDIMLSSASIFHLSFISID
RYYAVCDPLRYKAKMNILVICVMIFISWSVPAVFAFGMIFLELNFKGAEEIYYKHVHCRG
GCSVFFSKISGVLTFMTSFYIPGSIMLCVYYRIYLIAKEQARLISDANQKLQIGLEMKNG
ISQSKERKAVKTLGIVMGVFLICWCPFFICTVMDPFLHYIIPPTLNDVLIWFGYLNSTFN
PMVYAFFYPWFRKALKMMLFGKIFQKDSSRCKLFLELSS
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| BDBM50359505 |
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| n/a |
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| Name | BDBM50359505 |
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| Synonyms: | CHEMBL1182312 |
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| Type | Small organic molecule |
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| Emp. Form. | C14H14INO2 |
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| Mol. Mass. | 355.1709 |
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| SMILES | NCCc1ccc(Oc2ccc(O)cc2)c(I)c1 |
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| Structure | 
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