| Reaction Details |
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 | Report a problem with these data |
| Target | Beta-lactamase |
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| Ligand | BDBM50149781 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302784 (CHEMBL839469) |
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| Ki | 3000±n/a nM |
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| Citation |  Buzzoni, V; Blazquez, J; Ferrari, S; Calò, S; Venturelli, A; Costi, MP Aza-boronic acids as non-beta-lactam inhibitors of AmpC-beta-lactamase. Bioorg Med Chem Lett14:3979-83 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Beta-lactamase |
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| Name: | Beta-lactamase |
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| Synonyms: | AMPC_ECOLI | Beta-lactamase | Beta-lactamase (AmpC) | Beta-lactamase AmpC | Cephalosporinase | Escherichia coli K-12 | ampA | ampC |
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| Type: | Protien |
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| Mol. Mass.: | 41561.62 |
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| Organism: | Escherichia coli |
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| Description: | P00811 |
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| Residue: | 377 |
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| Sequence: | MFKTTLCALLITASCSTFAAPQQINDIVHRTITPLIEQQKIPGMAVAVIYQGKPYYFTWG
YADIAKKQPVTQQTLFELGSVSKTFTGVLGGDAIARGEIKLSDPTTKYWPELTAKQWNGI
TLLHLATYTAGGLPLQVPDEVKSSSDLLRFYQNWQPAWAPGTQRLYANSSIGLFGALAVK
PSGLSFEQAMQTRVFQPLKLNHTWINVPPAEEKNYAWGYREGKAVHVSPGALDAEAYGVK
STIEDMARWVQSNLKPLDINEKTLQQGIQLAQSRYWQTGDMYQGLGWEMLDWPVNPDSII
NGSDNKIALAARPVKAITPPTPAVRASWVHKTGATGGFGSYVAFIPEKELGIVMLANKNY
PNPARVDAAWQILNALQ
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|
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| BDBM50149781 |
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| n/a |
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| Name | BDBM50149781 |
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| Synonyms: | Aza-boronic acid derivative | CHEMBL368033 |
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| Type | Small organic molecule |
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| Emp. Form. | C12H10BBrN2O3 |
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| Mol. Mass. | 320.934 |
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| SMILES | OB(O)c1cc(ccc1O)N=Nc1ccc(Br)cc1 |w:11.12| |
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| Structure | 
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