| Reaction Details |
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 | Report a problem with these data |
| Target | Lysophosphatidic acid receptor 3 |
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| Ligand | BDBM50149996 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_304755 (CHEMBL829353) |
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| Ki | 39±n/a nM |
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| Citation |  Heasley, BH; Jarosz, R; Carter, KM; Van, SJ; Lynch, KR; Macdonald, TL A novel series of 2-pyridyl-containing compounds as lysophosphatidic acid receptor antagonists: development of a nonhydrolyzable LPA3 receptor-selective antagonist. Bioorg Med Chem Lett14:4069-74 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Lysophosphatidic acid receptor 3 |
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| Name: | Lysophosphatidic acid receptor 3 |
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| Synonyms: | EDG7 | LPA3 | LPAR3 | LPAR3_HUMAN | Lysophosphatidic acid receptor 1/3 | Lysophosphatidic acid receptor 3 (LPAR3) | Lysophosphatidic acid receptor Edg-7 |
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| Type: | Enzyme |
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| Mol. Mass.: | 40149.72 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q9UBY5 |
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| Residue: | 353 |
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| Sequence: | MNECHYDKHMDFFYNRSNTDTVDDWTGTKLVIVLCVGTFFCLFIFFSNSLVIAAVIKNRK
FHFPFYYLLANLAAADFFAGIAYVFLMFNTGPVSKTLTVNRWFLRQGLLDSSLTASLTNL
LVIAVERHMSIMRMRVHSNLTKKRVTLLILLVWAIAIFMGAVPTLGWNCLCNISACSSLA
PIYSRSYLVFWTVSNLMAFLIMVVVYLRIYVYVKRKTNVLSPHTSGSISRRRTPMKLMKT
VMTVLGAFVVCWTPGLVVLLLDGLNCRQCGVQHVKRWFLLLALLNSVVNPIIYSYKDEDM
YGTMKKMICCFSQENPERRPSRIPSTVLSRSDTGSQYIEDSISQGAVCNKSTS
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| BDBM50149996 |
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| n/a |
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| Name | BDBM50149996 |
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| Synonyms: | CHEMBL183143 | Phosphoric acid mono-[3-[4-(4-ethoxy-pyridin-2-ylmethoxy)-phenyl]-2-((Z)-(R)-octadec-9-enoylamino)-propyl] ester |
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| Type | Small organic molecule |
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| Emp. Form. | C35H55N2O7P |
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| Mol. Mass. | 646.7942 |
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| SMILES | CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](COP(O)(O)=O)Cc1ccc(OCc2cc(OCC)ccn2)cc1 |
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| Structure | 
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