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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Monoglyceride lipase | ||
| Ligand | BDBM50582222 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_2153726 (CHEMBL5038273) | ||
| IC50 | 0.024000±n/a nM | ||
| Citation |  Abdel-Magid, AF Therapeutic Potential of Monoacylglycerol Lipase (MGL) Inhibitors as Treatment for Pain, Depression, Cancers, and Eye Conditions. ACS Med Chem Lett13:22-24 (2022) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Monoglyceride lipase | |||
| Name: | Monoglyceride lipase | ||
| Synonyms: | HU-K5 | Lysophospholipase homolog | Lysophospholipase-like | MAGL | MGL | MGLL | MGLL_HUMAN | ||
| Type: | Hydrolase | ||
| Mol. Mass.: | 33264.56 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Human recombinant MGL (Cayman Chemical, cat# 10008354). | ||
| Residue: | 303 | ||
| Sequence: |
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| BDBM50582222 | |||
| n/a | |||
| Name | BDBM50582222 | ||
| Synonyms: | CHEMBL5074982 | US11708359, Example 71 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H28N2O3 | ||
| Mol. Mass. | 380.48 | ||
| SMILES | CC1(CC1)c1cccc(c1)C12CC1CN(CC2)C(=O)[C@H]1C[C@@]2(C1)COC(=O)N2 |r,wU:21.32,19.22,(81.16,-28.5,;81.16,-26.95,;81.56,-25.46,;82.65,-26.55,;79.83,-26.18,;78.5,-26.95,;77.17,-26.18,;77.18,-24.64,;78.52,-23.89,;79.83,-24.65,;78.52,-22.35,;79.85,-21.58,;78.52,-20.82,;77.18,-20.04,;75.86,-20.82,;75.85,-22.36,;77.18,-23.13,;74.53,-20.05,;74.53,-18.51,;73.2,-20.82,;72.8,-22.31,;71.31,-21.91,;71.71,-20.42,;70.99,-23.42,;69.45,-23.58,;68.82,-22.17,;67.31,-21.85,;69.97,-21.14,)| | ||
| Structure | 
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