Reaction Details |
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Target | Putative cathepsin L 3 |
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Ligand | BDBM50153291 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_305344 (CHEMBL832724) |
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IC50 | >250000±n/a nM |
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Citation | Chircorian, A; Barrios, AM Inhibition of lysosomal cysteine proteases by chrysotherapeutic compounds: a possible mechanism for the antiarthritic activity of Au(I). Bioorg Med Chem Lett14:5113-6 (2004) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Putative cathepsin L 3 |
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Name: | Putative cathepsin L 3 |
Synonyms: | CATL3_PARTE | Cathepsin L2 |
Type: | PROTEIN |
Mol. Mass.: | 35182.45 |
Organism: | Paramecium tetraurelia |
Description: | ChEMBL_302746 |
Residue: | 308 |
Sequence: | MKQFLTAAIVTLLMTAGYYHLQEDDTNDFERWALKNNKFYTESEKLYRMEIYNSNKRMIE
EHNQREDVTYQMGENQFMTLSHEEFVDLYLQKSDSSVNIMGASLPEVQLEGLGAVDWRNY
TTVKEQGQCASGWAFSVSNSLEAWYAIRGFQKINASTQQIVDCDYNNTGCSGGYNAYAME
YVLRVGLVSSTNYPYVAKNQTCKQSRNGTYFINGYSFVGGSQSNLQYYLNNYPISVGVEA
SNWQFYRSGLFSNCSSNGTNHYALAVGFDSANNWIVQNSWGTQWGESGNIRLYPQNTCGI
LNYPYQVY
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BDBM50153291 |
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n/a |
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Name | BDBM50153291 |
Synonyms: | (1-Thio-beta-D-glucopyranosato)(triethylphosphine)gold2,3,4,6-tetraacetate | AURANOFIN | CHEMBL1366 | Ridaura | SK&F-39162 | SK-39162 |
Type | Small organic molecule |
Emp. Form. | C20H34AuO9PS |
Mol. Mass. | 678.484 |
SMILES | CC[P+](CC)(CC)[Au-]S[C@@H]1O[C@H](COC(C)=O)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@H]1OC(C)=O |
Structure |
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