| Reaction Details |
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 | Report a problem with these data |
| Target | Melatonin receptor type 1A |
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| Ligand | BDBM50153424 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303582 (CHEMBL828981) |
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| Ki | 2.4±n/a nM |
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| Citation |  Sun, LQ; Takaki, K; Chen, J; Iben, L; Knipe, JO; Pajor, L; Mahle, CD; Ryan, E; Xu, C N-[2-[2-(4-Phenylbutyl)benzofuran-4-yl]cyclopropylmethyl]acetamide: an orally bioavailable melatonin receptor agonist. Bioorg Med Chem Lett14:5157-60 (2004) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Melatonin receptor type 1A |
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| Name: | Melatonin receptor type 1A |
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| Synonyms: | MTNR1A | MTNR1A protein | MTR1A_HUMAN | Mel-1A-R | Mel1a melatonin receptor | Melatonin 1A | Melatonin receptor | Melatonin receptor 1A | Melatonin receptor type 1 (MT1) | Melatonin receptor type 1A |
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| Type: | Enzyme |
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| Mol. Mass.: | 39392.94 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P48039 |
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| Residue: | 350 |
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| Sequence: | MQGNGSALPNASQPVLRGDGARPSWLASALACVLIFTIVVDILGNLLVILSVYRNKKLRN
AGNIFVVSLAVADLVVAIYPYPLVLMSIFNNGWNLGYLHCQVSGFLMGLSVIGSIFNITG
IAINRYCYICHSLKYDKLYSSKNSLCYVLLIWLLTLAAVLPNLRAGTLQYDPRIYSCTFA
QSVSSAYTIAVVVFHFLVPMIIVIFCYLRIWILVLQVRQRVKPDRKPKLKPQDFRNFVTM
FVVFVLFAICWAPLNFIGLAVASDPASMVPRIPEWLFVASYYMAYFNSCLNAIIYGLLNQ
NFRKEYRRIIVSLCTARVFFVDSSNDVADRVKWKPSPLMTNNNVVKVDSV
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| BDBM50153424 |
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| n/a |
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| Name | BDBM50153424 |
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| Synonyms: | CHEMBL186977 | N-{(S)-1-[2-(4-Phenyl-butyl)-benzofuran-4-yl]-pyrrolidin-3-yl}-propionamide |
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| Type | Small organic molecule |
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| Emp. Form. | C25H30N2O2 |
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| Mol. Mass. | 390.5179 |
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| SMILES | CCC(=O)N[C@H]1CCN(C1)c1cccc2oc(CCCCc3ccccc3)cc12 |
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| Structure | 
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