| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A2a |
|---|
| Ligand | BDBM50585022 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2161285 (CHEMBL5046035) |
|---|
| Ki | 448±n/a nM |
|---|
| Citation |  Tang, ML; Wen, ZH; Wang, JH; Wang, ML; Zhang, H; Liu, XH; Jin, L; Chang, J Discovery of Pyridone-Substituted Triazolopyrimidine Dual A ACS Med Chem Lett13:436-442 (2022) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A2a |
|---|
| Name: | Adenosine receptor A2a |
|---|
| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 44716.46 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P29274 |
|---|
| Residue: | 412 |
|---|
| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
|
|
|
|---|
| BDBM50585022 |
|---|
| n/a |
|---|
| Name | BDBM50585022 |
|---|
| Synonyms: | CHEMBL5076059 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C16H14N6O2 |
|---|
| Mol. Mass. | 322.3214 |
|---|
| SMILES | Cc1ccc(o1)-c1nc2c(cnc(N)n2n1)-c1ccc(=O)n(C)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
