| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Pantothenate kinase 3 |
|---|
| Ligand | BDBM50586904 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2170243 (CHEMBL5055302) |
|---|
| IC50 | 220±n/a nM |
|---|
| Citation |  Sharma, LK; Yun, MK; Subramanian, C; Tangallapally, R; Jackowski, S; Rock, CO; White, SW; Lee, RE LipE guided discovery of isopropylphenyl pyridazines as pantothenate kinase modulators. Bioorg Med Chem52:0 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Pantothenate kinase 3 |
|---|
| Name: | Pantothenate kinase 3 |
|---|
| Synonyms: | PANK3 | PANK3_HUMAN | Pantothenate kinase 3 | Pantothenic acid kinase 3 | hPanK3 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 41093.59 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_109587 |
|---|
| Residue: | 370 |
|---|
| Sequence: | MKIKDAKKPSFPWFGMDIGGTLVKLSYFEPIDITAEEEQEEVESLKSIRKYLTSNVAYGS
TGIRDVHLELKDLTLFGRRGNLHFIRFPTQDLPTFIQMGRDKNFSTLQTVLCATGGGAYK
FEKDFRTIGNLHLHKLDELDCLVKGLLYIDSVSFNGQAECYYFANASEPERCQKMPFNLD
DPYPLLVVNIGSGVSILAVHSKDNYKRVTGTSLGGGTFLGLCSLLTGCESFEEALEMASK
GDSTQADKLVRDIYGGDYERFGLPGWAVASSFGNMIYKEKRESVSKEDLARATLVTITNN
IGSVARMCAVNEKINRVVFVGNFLRVNTLSMKLLAYALDYWSKGQLKALFLEHEGYFGAV
GALLGLPNFS
|
|
|
|---|
| BDBM50586904 |
|---|
| n/a |
|---|
| Name | BDBM50586904 |
|---|
| Synonyms: | CHEMBL5070550 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H23ClN4O |
|---|
| Mol. Mass. | 358.865 |
|---|
| SMILES | CC(C)c1ccc(NC(=O)N2CCN(CC2)c2ccc(Cl)cn2)cc1 |
|---|
| Structure | 
|
|---|
Search and Browse
