| Reaction Details |
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 | Report a problem with these data |
| Target | Corticotropin-releasing factor receptor 1 |
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| Ligand | BDBM50158980 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_304278 (CHEMBL829879) |
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| EC50 | 98±n/a nM |
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| Citation |  Isfort, RJ; Wang, F; Tscheiner, M; Donnelly, E; Bauer, MB; Lefever, F; Hinkle, RT; Mazur, AW Discovery of corticotropin releasing factor 2 receptor selective sauvagine analogues for treatment of skeletal muscle atrophy. J Med Chem48:262-5 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Corticotropin-releasing factor receptor 1 |
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| Name: | Corticotropin-releasing factor receptor 1 |
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| Synonyms: | CRF-R | CRF1 | CRFR1_MOUSE | CRH-R 1 | Corticotropin releasing factor receptor 1 | Corticotropin-releasing hormone receptor 1 | Crhr | Crhr1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 47795.13 |
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| Organism: | MOUSE |
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| Description: | CRF1 CRHR1 MOUSE::P35347 |
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| Residue: | 415 |
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| Sequence: | MGQRPQLRLVKALLLLGLNPVSTSLQDQQCESLSLASNVSGLQCNASVDLIGTCWPRSPA
GQLVVRPCPAFFYGVRYNTTNNGYRECLANGSWAARVNYSECQEILNEEKKSKVHYHIAV
IINYLGHCISLVALLVAFVLFLRLRSIRCLRNIIHWNLISAFILRNATWFVVQLTVSPEV
HQSNVAWCRLVTAAYNYFHVTNFFWMFGEGCYLHTAIVLTYSTDRLRKWMFVCIGWGVPF
PIIVAWAIGKLYYDNEKCWFGKRPGVYTDYIYQGPMILVLLINFIFLFNIVRILMTKLRA
STTSETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDEVSRVVFIYFNSFLESFQGFFVS
VFYCFLNSEVRSAIRKRWRRWQDKHSIRARVARAMSIPTSPTRVSFHSIKQSTAV
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| BDBM50158980 |
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| n/a |
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| Name | BDBM50158980 |
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| Synonyms: | CHEMBL410347 | Sauvagine derivative |
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| Type | Small organic molecule |
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| Emp. Form. | C210H350N56O61S |
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| Mol. Mass. | 4667.43 |
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| SMILES | n/a |
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| Structure | 
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