| Reaction Details |
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 | Report a problem with these data |
| Target | Corticotropin-releasing factor receptor 2 |
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| Ligand | BDBM50119607 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_304279 (CHEMBL829880) |
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| EC50 | 49±n/a nM |
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| Citation |  Isfort, RJ; Wang, F; Tscheiner, M; Donnelly, E; Bauer, MB; Lefever, F; Hinkle, RT; Mazur, AW Discovery of corticotropin releasing factor 2 receptor selective sauvagine analogues for treatment of skeletal muscle atrophy. J Med Chem48:262-5 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Corticotropin-releasing factor receptor 2 |
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| Name: | Corticotropin-releasing factor receptor 2 |
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| Synonyms: | CRF-R-2 | CRF-R2 | CRF-RB | CRFR-2 | CRFR2_MOUSE | CRH-R-2 | CRH-R2 | Corticotropin releasing factor receptor 2 | Corticotropin-releasing factor receptor 2 | Corticotropin-releasing hormone receptor 2 | Crf2r | Crhr2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 47628.12 |
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| Organism: | Mus musculus |
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| Description: | ChEMBL_51276 |
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| Residue: | 411 |
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| Sequence: | MDAALLLSLLEANCSLALAEELLLDGWGVPPDPEGPYTYCNTTLDQIGTCWPQSAPGALV
ERPCPEYFNGIKYNTTRNAYRECLENGTWASRVNYSHCEPILDDKQRKYDLHYRIALIVN
YLGHCVSVVALVAAFLLFLVLRSIRCLRNVIHWNLITTFILRNIAWFLLQLIDHEVHEGN
EVWCRCITTIFNYFVVTNFFWMFVEGCYLHTAIVMTYSTEHLRKWLFLFIGWCIPCPIII
AWAVGKLYYENEQCWFGKEAGDLVDYIYQGPVMLVLLINFVFLFNIVRILMTKLRASTTS
ETIQYRKAVKATLVLLPLLGITYMLFFVNPGEDDLSQIVFIYFNSFLQSFQGFFVSVFYC
FFNGEVRAALRKRWHRWQDHHALRVPVARAMSIPTSPTRISFHSIKQTAAV
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| BDBM50119607 |
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| n/a |
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| Name | BDBM50119607 |
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| Synonyms: | CHEMBL440057 | E G P P I S I D L S L E L L R K M I E I E K Q E K E K Q Q A A N N R L L L D T I I-NH2(r/h CRF) | Human corticotropin releasing factor |
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| Type | Small organic molecule |
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| Emp. Form. | C208H343N59O64S2 |
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| Mol. Mass. | 4758.436 |
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| SMILES | n/a |
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| Structure | 
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