| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Baculoviral IAP repeat-containing protein 2 |
|---|
| Ligand | BDBM50588301 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2186651 (CHEMBL5098733) |
|---|
| IC50 | 370±n/a nM |
|---|
| Citation |  Udompholkul, P; Baggio, C; Gambini, L; Alboreggia, G; Pellecchia, M Lysine Covalent Antagonists of Melanoma Inhibitors of Apoptosis Protein. J Med Chem64:16147-16158 (2021) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Baculoviral IAP repeat-containing protein 2 |
|---|
| Name: | Baculoviral IAP repeat-containing protein 2 |
|---|
| Synonyms: | API1 | BIRC2 | BIRC2_HUMAN | Baculoviral IAP repeat-containing protein 2 (cIAP1) | Cellular inhibitor of apoptosis 1 | Inhibitor of apoptosis protein 2 (cIAP1) | MIHB | RNF48 |
|---|
| Type: | Protein |
|---|
| Mol. Mass.: | 69900.47 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q13490 |
|---|
| Residue: | 618 |
|---|
| Sequence: | MHKTASQRLFPGPSYQNIKSIMEDSTILSDWTNSNKQKMKYDFSCELYRMSTYSTFPAGV
PVSERSLARAGFYYTGVNDKVKCFCCGLMLDNWKLGDSPIQKHKQLYPSCSFIQNLVSAS
LGSTSKNTSPMRNSFAHSLSPTLEHSSLFSGSYSSLSPNPLNSRAVEDISSSRTNPYSYA
MSTEEARFLTYHMWPLTFLSPSELARAGFYYIGPGDRVACFACGGKLSNWEPKDDAMSEH
RRHFPNCPFLENSLETLRFSISNLSMQTHAARMRTFMYWPSSVPVQPEQLASAGFYYVGR
NDDVKCFCCDGGLRCWESGDDPWVEHAKWFPRCEFLIRMKGQEFVDEIQGRYPHLLEQLL
STSDTTGEENADPPIIHFGPGESSSEDAVMMNTPVVKSALEMGFNRDLVKQTVQSKILTT
GENYKTVNDIVSALLNAEDEKREEEKEKQAEEMASDDLSLIRKNRMALFQQLTCVLPILD
NLLKANVINKQEHDIIKQKTQIPLQARELIDTILVKGNAAANIFKNCLKEIDSTLYKNLF
VDKNMKYIPTEDVSGLSLEEQLRRLQEERTCKVCMDKEVSVVFIPCGHLVVCQECAPSLR
KCPICRGIIKGTVRTFLS
|
|
|
|---|
| BDBM50588301 |
|---|
| n/a |
|---|
| Name | BDBM50588301 |
|---|
| Synonyms: | CHEMBL5195146 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C29H37N5O8S |
|---|
| Mol. Mass. | 615.698 |
|---|
| SMILES | CN[C@@H](C)C(=O)N[C@@H](CNC(=O)c1cc(ccc1OC)S(O)(=O)=O)C(=O)N1CCC[C@H]1C(=O)N[C@@H]1CCc2ccccc12 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
