| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Tubulin beta-2B chain |
|---|
| Ligand | BDBM50159534 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_312291 (CHEMBL837869) |
|---|
| IC50 | 13000±n/a nM |
|---|
| Citation |  Maya, AB; Pérez-Melero, C; Mateo, C; Alonso, D; Fernández, JL; Gajate, C; Mollinedo, F; Peláez, R; Caballero, E; Medarde, M Further naphthylcombretastatins. An investigation on the role of the naphthalene moiety. J Med Chem48:556-68 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Tubulin beta-2B chain |
|---|
| Name: | Tubulin beta-2B chain |
|---|
| Synonyms: | TBB2B_BOVIN | TUBB2B | Tubulin | Tubulin beta chain |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 49932.38 |
|---|
| Organism: | Bos taurus |
|---|
| Description: | ChEMBL_211651 |
|---|
| Residue: | 445 |
|---|
| Sequence: | MREIVHIQAGQCGNQIGAKFWEVISDEHGIDPTGSYHGDSDLQLERINVYYNEATGNKYV
PRAILVDLEPGTMDSVRSGPFGQIFRPDNFVFGQSGAGNNWAKGHYTEGAELVDSVLDVV
RKESESCDCLQGFQLTHSLGGGTGSGMGTLLISKIREEYPDRIMNTFSVMPSPKVSDTVV
EPYNATLSVHQLVENTDETYCIDNEALYDICFRTLKLTTPTYGDLNHLVSATMSGVTTCL
RFPGQLNADLRKLAVNMVPFPRLHFFMPGFAPLTSRGSQQYRALTVPELTQQMFDSKNMM
AACDPRHGRYLTVAAIFRGRMSMKEVDEQMLNVQNKNSSYFVEWIPNNVKTAVCDIPPRG
LKMSATFIGNSTAIQELFKRISEQFTAMFRRKAFLHWYTGEGMDEMEFTEAESNMNDLVS
EYQQYQDATADEQGEFEEEEGEDEA
|
|
|
|---|
| BDBM50159534 |
|---|
| n/a |
|---|
| Name | BDBM50159534 |
|---|
| Synonyms: | 2-[(Z)-2-(3,4-Dimethoxy-5-nitro-phenyl)-vinyl]-naphthalene | CHEMBL180024 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H17NO4 |
|---|
| Mol. Mass. | 335.3533 |
|---|
| SMILES | COc1cc(\C=C/c2ccc3ccccc3c2)cc(c1OC)[N+]([O-])=O |
|---|
| Structure | 
|
|---|
Search and Browse
