| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Metabotropic glutamate receptor 7 |
|---|
| Ligand | BDBM50589650 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2193961 (CHEMBL5106321) |
|---|
| IC50 | 263±n/a nM |
|---|
| Citation |  Reed, CW; Rodriguez, AL; Kalbfleisch, JJ; Seto, M; Jenkins, MT; Blobaum, AL; Chang, S; Lindsley, CW; Niswender, CM Development and profiling of mGlu Bioorg Med Chem Lett74:0 (2022) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Metabotropic glutamate receptor 7 |
|---|
| Name: | Metabotropic glutamate receptor 7 |
|---|
| Synonyms: | GRM7_RAT | Gprc1g | Grm7 | Metabotropic glutamate receptor | Metabotropic glutamate receptor 7 (mGlu7) | Mglur7 | mGlu7 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 102244.48 |
|---|
| Organism: | Rattus norvegicus (Rat) |
|---|
| Description: | P35400 |
|---|
| Residue: | 915 |
|---|
| Sequence: | MVQLGKLLRVLTLMKFPCCVLEVLLCVLAAAARGQEMYAPHSIRIEGDVTLGGLFPVHAK
GPSGVPCGDIKRENGIHRLEAMLYALDQINSDPNLLPNVTLGARILDTCSRDTYALEQSL
TFVQALIQKDTSDVRCTNGEPPVFVKPEKVVGVIGASGSSVSIMVANILRLFQIPQISYA
STAPELSDDRRYDFFSRVVPPDSFQAQAMVDIVKALGWNYVSTLASEGSYGEKGVESFTQ
ISKEAGGLCIAQSVRIPQERKDRTIDFDRIIKQLLDTPNSRAVVIFANDEDIKQILAAAK
RADQVGHFLWVGSDSWGSKINPLHQHEDIAEGAITIQPKRATVEGFDAYFTSRTLENNRR
NVWFAEYWEENFNCKLTISGSKKEDTDRKCTGQERIGKDSNYEQEGKVQFVIDAVYAMAH
ALHHMNKDLCADYRGVCPEMEQAGGKKLLKYIRHVNFNGSAGTPVMFNKNGDAPGRYDIF
QYQTTNTTNPGYRLIGQWTDELQLNIEDMQWGKGVREIPSSVCTLPCKPGQRKKTQKGTP
CCWTCEPCDGYQYQFDEMTCQHCPYDQRPNENRTGCQNIPIIKLEWHSPWAVIPVFLAML
GIIATIFVMATFIRYNDTPIVRASGRELSYVLLTGIFLCYIITFLMIAKPDVAVCSFRRV
FLGLGMCISYAALLTKTNRIYRIFEQGKKSVTAPRLISPTSQLAITSSLISVQLLGVFIW
FGVDPPNIIIDYDEHKTMNPEQARGVLKCDITDLQIICSLGYSILLMVTCTVYAIKTRGV
PENFNEAKPIGFTMYTTCIVWLAFIPIFFGTAQSAEKLYIQTTTLTISMNLSASVALGML
YMPKVYIIIFHPELNVQKRKRSFKAVVTAATMSSRLSHKPSDRPNGEAKTELCENVDPNS
PAAKKKYVSYNNLVI
|
|
|
|---|
| BDBM50589650 |
|---|
| n/a |
|---|
| Name | BDBM50589650 |
|---|
| Synonyms: | CHEMBL5202961 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H19F3N4O6 |
|---|
| Mol. Mass. | 480.394 |
|---|
| SMILES | COc1cc(OCC(=O)Nc2cc(OC(F)(F)F)ccc2-n2cncn2)ccc1OC1COC1 |
|---|
| Structure | 
|
|---|
Search and Browse
