| Reaction Details |
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 | Report a problem with these data |
| Target | Serpin H1 |
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| Ligand | BDBM50162505 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_305934 (CHEMBL833481) |
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| IC50 | 3100±n/a nM |
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| Citation |  Thomson, CA; Atkinson, HM; Ananthanarayanan, VS Identification of small molecule chemical inhibitors of the collagen-specific chaperone Hsp47. J Med Chem48:1680-4 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Serpin H1 |
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| Name: | Serpin H1 |
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| Synonyms: | CBP1 | CBP2 | Collagen-binding protein 1 | HSP47 | SERPH_HUMAN | SERPINH1 | SERPINH2 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46451.09 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_305934 |
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| Residue: | 418 |
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| Sequence: | MRSLLLLSAFCLLEAALAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAK
DQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSN
STARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQT
TDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRT
GLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKK
AVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELD
TDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL
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| BDBM50162505 |
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| n/a |
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| Name | BDBM50162505 |
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| Synonyms: | 6-Chloro-2-oxo-2,3-dihydro-2lambda*4*-benzo[1,2,3]dithiazole-4-carboxylic acid methyl ester | CHEMBL371508 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H6ClNO3S2 |
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| Mol. Mass. | 263.721 |
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| SMILES | COC(=O)c1cc(Cl)cc2SS(=O)Nc12 |
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| Structure | 
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