| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM50590626 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2197332 (CHEMBL5109848) |
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| Ki | 22±n/a nM |
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| Citation |  Bolteau, R; Duroux, R; Laversin, A; Vreulz, B; Shiriaeva, A; Stauch, B; Han, GW; Cherezov, V; Renault, N; Barczyk, A; Ravez, S; Coevoet, M; Melnyk, P; Liberelle, M; Yous, S High ligand efficiency quinazoline compounds as novel A Eur J Med Chem241:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM50590626 |
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| n/a |
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| Name | BDBM50590626 |
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| Synonyms: | CHEMBL5199840 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H11N3O |
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| Mol. Mass. | 225.2459 |
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| SMILES | Cc1ccc2nc(N)nc(-c3ccco3)c2c1 |
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| Structure | 
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