| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM35254 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303245 (CHEMBL827210) |
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| Ki | 39±n/a nM |
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| Citation |  Campiani, G; Butini, S; Fattorusso, C; Trotta, F; Gemma, S; Catalanotti, B; Nacci, V; Fiorini, I; Cagnotto, A; Mereghetti, I; Mennini, T; Minetti, P; Di Cesare, MA; Stasi, MA; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Novel atypical antipsychotic agents: rational design, an efficient palladium-catalyzed route, and pharmacological studies. J Med Chem48:1705-8 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DOPAMINE D3 | DRD3 | DRD3_HUMAN | Dopamine D3 receptor | Dopamine D3 receptor (D3) | Dopamine D3 receptor (D3R) | Dopamine receptor | Dopamine receptor (D3) | Dopamine receptor D3 |
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| Type: | n/a |
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| Mol. Mass.: | 44243.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 400 |
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| Sequence: | MASLSQLSSHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM35254 |
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| n/a |
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| Name | BDBM35254 |
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| Synonyms: | 2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine | CHEMBL715 | Olansek | US8802672, Olanzapine | Zyprexa | olanzapine |
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| Type | Small organic molecule |
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| Emp. Form. | C17H20N4S |
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| Mol. Mass. | 312.432 |
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| SMILES | CN1CCN(CC1)C1=Nc2ccccc2Nc2sc(C)cc12 |t:8| |
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| Structure | 
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