| Reaction Details |
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 | Report a problem with these data |
| Target | D(1A) dopamine receptor |
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| Ligand | BDBM50162952 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303034 (CHEMBL828862) |
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| Ki | 125±n/a nM |
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| Citation |  Campiani, G; Butini, S; Fattorusso, C; Trotta, F; Gemma, S; Catalanotti, B; Nacci, V; Fiorini, I; Cagnotto, A; Mereghetti, I; Mennini, T; Minetti, P; Di Cesare, MA; Stasi, MA; Di Serio, S; Ghirardi, O; Tinti, O; Carminati, P Novel atypical antipsychotic agents: rational design, an efficient palladium-catalyzed route, and pharmacological studies. J Med Chem48:1705-8 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1A) dopamine receptor |
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| Name: | D(1A) dopamine receptor |
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| Synonyms: | DOPAMINE D1 | DRD1_RAT | Dopamine D1 high | Dopamine D1 low | Dopamine receptor | Dopamine receptor D1 | Dopamine1-like | Drd1 | Drd1a |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 49429.75 |
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| Organism: | RAT |
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| Description: | P18901 |
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| Residue: | 446 |
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| Sequence: | MAPNTSTMDEAGLPAERDFSFRILTACFLSLLILSTLLGNTLVCAAVIRFRHLRSKVTNF
FVISLAVSDLLVAVLVMPWKAVAEIAGFWPLGPFCNIWVAFDIMCSTASILNLCVISVDR
YWAISSPFQYERKMTPKAAFILISVAWTLSVLISFIPVQLSWHKAKPTWPLDGNFTSLED
TEDDNCDTRLSRTYAISSSLISFYIPVAIMIVTYTSIYRIAQKQIRRISALERAAVHAKN
CQTTAGNGNPVECAQSESSFKMSFKRETKVLKTLSVIMGVFVCCWLPFFISNCMVPFCGS
EETQPFCIDSITFDVFVWFGWANSSLNPIIYAFNADFQKAFSTLLGCYRLCPTTNNAIET
VSINNNGAVVFSSHHEPRGSISKDCNLVYLIPHAVGSSEDLKKEEAGGIAKPLEKLSPAL
SVILDYDTDVSLEKIQPVTHSGQHST
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| BDBM50162952 |
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| n/a |
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| Name | BDBM50162952 |
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| Synonyms: | 11-(4-Methyl-piperazin-1-yl)-5H-benzo[e]pyrrolo[1,2-a]azepine | CHEMBL179775 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H21N3 |
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| Mol. Mass. | 279.3794 |
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| SMILES | CN1CCN(CC1)C1=Cc2ccccc2Cn2cccc12 |t:8| |
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| Structure | 
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