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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Wee1-like protein kinase | ||
| Ligand | BDBM50164141 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_304894 (CHEMBL829373) | ||
| IC50 | 1000±n/a nM | ||
| Citation |  Palmer, BD; Smaill, JB; Rewcastle, GW; Dobrusin, EM; Kraker, A; Moore, CW; Steinkampf, RW; Denny, WA Structure-activity relationships for 2-anilino-6-phenylpyrido[2,3-d]pyrimidin-7(8H)-ones as inhibitors of the cellular checkpoint kinase Wee1. Bioorg Med Chem Lett15:1931-5 (2005) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Wee1-like protein kinase | |||
| Name: | Wee1-like protein kinase | ||
| Synonyms: | Serine/threonine-protein kinase WEE1 | WEE1 | WEE1 homolog (S. pombe) | WEE1_HUMAN | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 71599.12 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | ChEMBL_1445054 | ||
| Residue: | 646 | ||
| Sequence: |
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| BDBM50164141 | |||
| n/a | |||
| Name | BDBM50164141 | ||
| Synonyms: | 6-(3,5-Dihydroxy-2,6-dimethyl-phenyl)-8-methyl-2-phenylamino-8H-pyrido[2,3-d]pyrimidin-7-one | CHEMBL178439 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H20N4O3 | ||
| Mol. Mass. | 388.4192 | ||
| SMILES | Cc1c(O)cc(O)c(C)c1-c1cc2cnc(Nc3ccccc3)nc2n(C)c1=O |(2.13,3.27,;3.47,2.52,;4.8,3.3,;4.78,4.84,;6.16,2.53,;6.16,.98,;7.49,.23,;4.82,.21,;4.82,-1.33,;3.49,.98,;2.16,.2,;.82,.96,;-.51,.19,;-1.84,.96,;-3.17,.18,;-3.17,-1.36,;-4.5,-2.15,;-5.86,-1.38,;-5.84,.16,;-7.19,.94,;-8.53,.16,;-8.5,-1.39,;-7.17,-2.15,;-1.84,-2.14,;-.51,-1.34,;.83,-2.13,;.83,-3.66,;2.16,-1.34,;3.52,-2.11,)| | ||
| Structure | 
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