| Reaction Details |
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 | Report a problem with these data |
| Target | UDP-galactopyranose mutase |
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| Ligand | BDBM50592578 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2204529 (CHEMBL5117237) |
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| Kd | 104800±n/a nM |
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| Citation |  Fu, J; He, Z; Fu, H; Xia, Y; N'Go, I; Lou, H; Wu, J; Pan, W; Vincent, SP Synthesis and evaluation of inhibitors of Mycobacterium tuberculosis UGM using bioisosteric replacement. Bioorg Med Chem69:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| UDP-galactopyranose mutase |
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| Name: | UDP-galactopyranose mutase |
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| Synonyms: | GLF_MYCTU | UDP-galactopyranose mutase | Uridine 5'-diphosphate-galactopyranose mutase (UGM) | glf |
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| Type: | Protein |
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| Mol. Mass.: | 45807.82 |
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| Organism: | Mycobacterium tuberculosis H37Rv |
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| Description: | P9WIQ1 |
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| Residue: | 399 |
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| Sequence: | MQPMTARFDLFVVGSGFFGLTIAERVATQLDKRVLVLERRPHIGGNAYSEAEPQTGIEVH
KYGAHLFHTSNKRVWDYVRQFTDFTDYRHRVFAMHNGQAYQFPMGLGLVSQFFGKYFTPE
QARQLIAEQAAEIDTADAQNLEEKAISLIGRPLYEAFVKGYTAKQWQTDPKELPAANITR
LPVRYTFDNRYFSDTYEGLPTDGYTAWLQNMAADHRIEVRLNTDWFDVRGQLRPGSPAAP
VVYTGPLDRYFDYAEGRLGWRTLDFEVEVLPIGDFQGTAVMNYNDLDVPYTRIHEFRHFH
PERDYPTDKTVIMREYSRFAEDDDEPYYPINTEADRALLATYRARAKSETASSKVLFGGR
LGTYQYLDMHMAIASALNMYDNVLAPHLRDGVPLLQDGA
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| BDBM50592578 |
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| n/a |
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| Name | BDBM50592578 |
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| Synonyms: | CHEMBL5205229 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H16BrNO3 |
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| Mol. Mass. | 374.229 |
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| SMILES | OC(=O)[C@H](Cc1ccc(Br)cc1)NC(=O)\C=C\c1ccccc1 |r| |
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| Structure | 
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