| Reaction Details |
|---|
 | Report a problem with these data |
| Target | B-cell receptor CD22 |
|---|
| Ligand | BDBM50592890 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2205928 (CHEMBL5118636) |
|---|
| IC50 | 0.320000±n/a nM |
|---|
| Citation |  Prescher, H; Schweizer, A; Frank, M; Kuhfeldt, E; Ring, J; Nitschke, L Targeting J Med Chem65:10588-10610 (2022) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| B-cell receptor CD22 |
|---|
| Name: | B-cell receptor CD22 |
|---|
| Synonyms: | CD22 | CD22_HUMAN | SIGLEC2 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 95348.60 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_727026 |
|---|
| Residue: | 847 |
|---|
| Sequence: | MHLLGPWLLLLVLEYLAFSDSSKWVFEHPETLYAWEGACVWIPCTYRALDGDLESFILFH
NPEYNKNTSKFDGTRLYESTKDGKVPSEQKRVQFLGDKNKNCTLSIHPVHLNDSGQLGLR
MESKTEKWMERIHLNVSERPFPPHIQLPPEIQESQEVTLTCLLNFSCYGYPIQLQWLLEG
VPMRQAAVTSTSLTIKSVFTRSELKFSPQWSHHGKIVTCQLQDADGKFLSNDTVQLNVKH
TPKLEIKVTPSDAIVREGDSVTMTCEVSSSNPEYTTVSWLKDGTSLKKQNTFTLNLREVT
KDQSGKYCCQVSNDVGPGRSEEVFLQVQYAPEPSTVQILHSPAVEGSQVEFLCMSLANPL
PTNYTWYHNGKEMQGRTEEKVHIPKILPWHAGTYSCVAENILGTGQRGPGAELDVQYPPK
KVTTVIQNPMPIREGDTVTLSCNYNSSNPSVTRYEWKPHGAWEEPSLGVLKIQNVGWDNT
TIACAACNSWCSWASPVALNVQYAPRDVRVRKIKPLSEIHSGNSVSLQCDFSSSHPKEVQ
FFWEKNGRLLGKESQLNFDSISPEDAGSYSCWVNNSIGQTASKAWTLEVLYAPRRLRVSM
SPGDQVMEGKSATLTCESDANPPVSHYTWFDWNNQSLPYHSQKLRLEPVKVQHSGAYWCQ
GTNSVGKGRSPLSTLTVYYSPETIGRRVAVGLGSCLAILILAICGLKLQRRWKRTQSQQG
LQENSSGQSFFVRNKKVRRAPLSEGPHSLGCYNPMMEDGISYTTLRFPEMNIPRTGDAES
SEMQRPPPDCDDTVTYSALHKRQVGDYENVIPDFPEDEGIHYSELIQFGVGERPQAQENV
DYVILKH
|
|
|
|---|
| BDBM50592890 |
|---|
| n/a |
|---|
| Name | BDBM50592890 |
|---|
| Synonyms: | CHEMBL5184174 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C36H42N3NaO10S |
|---|
| Mol. Mass. | 731.788 |
|---|
| SMILES | [Na;v0+].[H][C@]1([#8][C@@]([#6]-[#6@H](-[#8])-[#6@H]1-[#7]-[#6](-[#6])=O)([#8]-[#6]-[#6]-[#6]-[#16]-[#6]-[#6]-[#7]-[#6](=O)-c1ccccc1)[#6](-[#8-])=O)[#6@H](-[#8])-[#6@H](-[#8])-[#6]-[#7]-[#6](=O)-c1ccc(cc1)-c1ccccc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
