Reaction Details | |||
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Target | D(4) dopamine receptor | ||
Ligand | BDBM50166032 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | ChEMBL_303360 (CHEMBL838695) | ||
Ki | >10000±n/a nM | ||
Citation | Ding, K; Chen, J; Ji, M; Wu, X; Varady, J; Yang, CY; Lu, Y; Deschamps, JR; Levant, B; Wang, S Enantiomerically pure hexahydropyrazinoquinolines as potent and selective dopamine 3 subtype receptor ligands. J Med Chem48:3171-81 (2005) [PubMed] Article | ||
More Info.: | Get all data from this article, Assay Method | ||
D(4) dopamine receptor | |||
Name: | D(4) dopamine receptor | ||
Synonyms: | D(4) dopamine receptor | DOPAMINE D4 | DOPAMINE D4.4 | DRD4_RAT | Dopamine receptor | Drd4 | ||
Type: | Enzyme Catalytic Domain | ||
Mol. Mass.: | 41307.65 | ||
Organism: | RAT | ||
Description: | DOPAMINE D4.4 0 RAT::P30729 | ||
Residue: | 387 | ||
Sequence: |
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BDBM50166032 | |||
n/a | |||
Name | BDBM50166032 | ||
Synonyms: | CHEMBL191894 | Naphthalene-2-carboxylic acid {4-[2-((S)-8-methoxy-1,2,4,4a,5,6-hexahydro-pyrazino[1,2-a]quinolin-3-yl)-ethyl]-cyclohexyl}-amide | ||
Type | Small organic molecule | ||
Emp. Form. | C32H39N3O2 | ||
Mol. Mass. | 497.671 | ||
SMILES | COc1ccc2N3CCN(CCC4CCC(CC4)NC(=O)c4ccc5ccccc5c4)C[C@@H]3CCc2c1 |wU:32.35,(-5.22,2.89,;-3.9,3.66,;-2.54,2.93,;-2.52,1.37,;-1.19,.65,;.12,1.42,;1.48,.67,;1.42,-.85,;2.75,-1.66,;4.11,-.89,;5.65,-.87,;6.45,-2.2,;7.99,-2.18,;8.73,-.84,;10.27,-.82,;11.06,-2.15,;10.3,-3.48,;8.77,-3.51,;12.6,-2.13,;13.35,-.78,;12.56,.55,;14.89,-.77,;15.63,.58,;17.17,.61,;17.95,-.71,;19.47,-.68,;20.26,-1.98,;19.54,-3.32,;18,-3.36,;17.2,-2.06,;15.66,-2.08,;4.13,.67,;2.8,1.46,;2.78,3,;1.43,3.75,;.12,2.96,;-1.23,3.7,)| | ||
Structure |