| Reaction Details |
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 | Report a problem with these data |
| Target | D(1B) dopamine receptor |
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| Ligand | BDBM50166023 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302994 (CHEMBL830233) |
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| Ki | 4330±n/a nM |
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| Citation |  Ding, K; Chen, J; Ji, M; Wu, X; Varady, J; Yang, CY; Lu, Y; Deschamps, JR; Levant, B; Wang, S Enantiomerically pure hexahydropyrazinoquinolines as potent and selective dopamine 3 subtype receptor ligands. J Med Chem48:3171-81 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(1B) dopamine receptor |
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| Name: | D(1B) dopamine receptor |
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| Synonyms: | D(1B) dopamine receptor | DOPAMINE D5 | DRD5_RAT | Dopamine D1B | Dopamine D5 receptor | Dopamine receptor | Drd5 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 52827.88 |
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| Organism: | RAT |
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| Description: | Dopamine D1B 0 RAT::P25115 |
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| Residue: | 475 |
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| Sequence: | MLPPGRNRTAQPARLGLQRQLAQVDAPAGSATPLGPAQVVTAGLLTLLIVWTLLGNVLVC
AAIVRSRHLRAKMTNIFIVSLAVSDLFVALLVMPWKAVAEVAGYWPFGTFCDIWVAFDIM
CSTASILNLCIISVDRYWAISRPFRYERKMTQRVALVMVGLAWTLSILISFIPVQLNWHR
DKAGSQGQEGLLSNGTPWEEGWELEGRTENCDSSLNRTYAISSSLISFYIPVAIMIVTYT
RIYRIAQVQIRRISSLERAAEHAQSCRSRGAYEPDPSLRASIKKETKVFKTLSMIMGVFV
CCWLPFFILNCMVPFCSSGDAEGPKTGFPCVSETTFDIFVWFGWANSSLNPIIYAFNADF
RKVFAQLLGCSHFCFRTPVQTVNISNELISYNQDTVFHKEIATAYVHMIPNAVSSGDREV
GEEEEEGPFDHMSQISPTTPDGDLAAESVWELDCEEEVSLGKISPLTPNCFDKTA
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| BDBM50166023 |
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| n/a |
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| Name | BDBM50166023 |
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| Synonyms: | CHEMBL192439 | Naphthalene-2-carboxylic acid [4-((S)-9-methoxy-1,2,4,4a,5,6-hexahydro-pyrazino[1,2-a]quinolin-3-yl)-butyl]-amide |
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| Type | Small organic molecule |
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| Emp. Form. | C28H33N3O2 |
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| Mol. Mass. | 443.5805 |
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| SMILES | COc1ccc2CC[C@H]3CN(CCCCNC(=O)c4ccc5ccccc5c4)CCN3c2c1 |
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| Structure | 
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