| Reaction Details |
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 | Report a problem with these data |
| Target | Glutamate receptor 3 |
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| Ligand | BDBM50166288 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303111 (CHEMBL876377) |
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| Ki | 2.24±n/a nM |
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| Citation |  Vogensen, SB; Clausen, RP; Greenwood, JR; Johansen, TN; Pickering, DS; Nielsen, B; Ebert, B; Krogsgaard-Larsen, P Convergent synthesis and pharmacology of substituted tetrazolyl-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid analogues. J Med Chem48:3438-42 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Glutamate receptor 3 |
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| Name: | Glutamate receptor 3 |
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| Synonyms: | AMPA-selective glutamate receptor 3 | GLUR3 | GLURC | GRIA3 | GRIA3_HUMAN | GluR-3 | GluR-C | GluR-K3 | Glutamate receptor 3 | Glutamate receptor ionotropic AMPA | Glutamate receptor ionotropic, AMPA 3 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 101172.14 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_468627 |
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| Residue: | 894 |
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| Sequence: | MARQKKMGQSVLRAVFFLVLGLLGHSHGGFPNTISIGGLFMRNTVQEHSAFRFAVQLYNT
NQNTTEKPFHLNYHVDHLDSSNSFSVTNAFCSQFSRGVYAIFGFYDQMSMNTLTSFCGAL
HTSFVTPSFPTDADVQFVIQMRPALKGAILSLLGHYKWEKFVYLYDTERGFSILQAIMEA
AVQNNWQVTARSVGNIKDVQEFRRIIEEMDRRQEKRYLIDCEVERINTILEQVVILGKHS
RGYHYMLANLGFTDILLERVMHGGANITGFQIVNNENPMVQQFIQRWVRLDEREFPEAKN
APLKYTSALTHDAILVIAEAFRYLRRQRVDVSRRGSAGDCLANPAVPWSQGIDIERALKM
VQVQGMTGNIQFDTYGRRTNYTIDVYEMKVSGSRKAGYWNEYERFVPFSDQQISNDSASS
ENRTIVVTTILESPYVMYKKNHEQLEGNERYEGYCVDLAYEIAKHVRIKYKLSIVGDGKY
GARDPETKIWNGMVGELVYGRADIAVAPLTITLVREEVIDFSKPFMSLGISIMIKKPQKS
KPGVFSFLDPLAYEIWMCIVFAYIGVSVVLFLVSRFSPYEWHLEDNNEEPRDPQSPPDPP
NEFGIFNSLWFSLGAFMQQGCDISPRSLSGRIVGGVWWFFTLIIISSYTANLAAFLTVER
MVSPIESAEDLAKQTEIAYGTLDSGSTKEFFRRSKIAVYEKMWSYMKSAEPSVFTKTTAD
GVARVRKSKGKFAFLLESTMNEYIEQRKPCDTMKVGGNLDSKGYGVATPKGSALRNAVNL
AVLKLNEQGLLDKLKNKWWYDKGECGSGGGDSKDKTSALSLSNVAGVFYILVGGLGLAMM
VALIEFCYKSRAESKRMKLTKNTQNFKPAPATNTQNYATYREGYNVYGTESVKI
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| BDBM50166288 |
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| n/a |
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| Name | BDBM50166288 |
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| Synonyms: | (S)-2-Amino-3-[3-hydroxy-5-(2-methyl-2H-tetrazol-5-yl)-isoxazol-4-yl]-propionic acid | (S)-2-amino-3-[3-hydroxy-5-(2-methyl-2H-5-tetrazolyl)-4-isoxazolyl]propionic acid | CHEMBL370038 |
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| Type | Small organic molecule |
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| Emp. Form. | C8H10N6O4 |
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| Mol. Mass. | 254.2028 |
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| SMILES | Cn1nnc(n1)-c1o[nH]c(=O)c1C[C@H](N)C(O)=O |
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| Structure | 
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