| Reaction Details |
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 | Report a problem with these data |
| Target | Type-2 angiotensin II receptor |
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| Ligand | BDBM50594186 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2211258 (CHEMBL5124207) |
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| Ki | 1.4±n/a nM |
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| Citation |  Gopalan, G; Palo-Nieto, C; Petersen, NN; Hallberg, M; Larhed, M Angiotensin II AT2 receptor ligands with phenylthiazole scaffolds. Bioorg Med Chem65:0 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Type-2 angiotensin II receptor |
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| Name: | Type-2 angiotensin II receptor |
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| Synonyms: | AGTR2 | AGTR2_HUMAN | AT2 | Angiotensin II receptor | Angiotensin II type 2 (AT-2) receptor | Angiotensin II, central | Type-2 angiotensin II receptor |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 41201.61 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Angiotensin II, central 0 0::P50052 |
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| Residue: | 363 |
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| Sequence: | MKGNSTLATTSKNITSGLHFGLVNISGNNESTLNCSQKPSDKHLDAIPILYYIIFVIGFL
VNIVVVTLFCCQKGPKKVSSIYIFNLAVADLLLLATLPLWATYYSYRYDWLFGPVMCKVF
GSFLTLNMFASIFFITCMSVDRYQSVIYPFLSQRRNPWQASYIVPLVWCMACLSSLPTFY
FRDVRTIEYLGVNACIMAFPPEKYAQWSAGIALMKNILGFIIPLIFIATCYFGIRKHLLK
TNSYGKNRITRDQVLKMAAAVVLAFIICWLPFHVLTFLDALAWMGVINSCEVIAVIDLAL
PFAILLGFTNSCVNPFLYCFVGNRFQQKLRSVFRVPITWLQGKRESMSCRKSSSLREMET
FVS
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| BDBM50594186 |
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| n/a |
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| Name | BDBM50594186 |
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| Synonyms: | CHEMBL5174659 |
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| Type | Small organic molecule |
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| Emp. Form. | C21H21N5O4S3 |
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| Mol. Mass. | 503.618 |
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| SMILES | CCCc1nc(c(s1)S(=O)(=O)NC(=O)OC)-c1ccc(Cn2ccnc2-c2nccs2)cc1 |
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| Structure | 
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