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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Amyloid-beta precursor protein | ||
| Ligand | BDBM50595332 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_2216173 (CHEMBL5129305) | ||
| EC50 | 6.7±n/a nM | ||
| Citation |  Kubo, K; Watanabe, H; Kumeta, H; Aizawa, T; Seki, C; Nakano, H; Tokuraku, K; Uwai, K Chemical analysis of amyloid ? aggregation inhibitors derived from Geranium thunbergii. Bioorg Med Chem68:0 (2022) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Amyloid-beta precursor protein | |||
| Name: | Amyloid-beta precursor protein | ||
| Synonyms: | A4 | A4_HUMAN | ABPP | AD1 | AICD-50 | AICD-57 | AICD-59 | AID(50) | AID(57) | AID(59) | APP | APPI | Alzheimer disease amyloid protein | Amyloid beta A4 protein | Amyloid beta Protein | Amyloid beta protein (sAPPbeta) | Amyloid beta protein Abeta(1-42) | Amyloid intracellular domain 50 | Amyloid intracellular domain 57 | Amyloid intracellular domain 59 | Amyloid protein (Abeta42b) | Amyloid β-protein (Aβ42) | Beta amyloid A4 protein | Beta-APP40 | Beta-APP42 | Beta-amyloid protein 40 | Beta-amyloid protein 42 | C31 | C83 | C99 | CVAP | Cerebral vascular amyloid peptide | Gamma Secretase | Gamma-CTF(50) | Gamma-CTF(57) | Gamma-CTF(59) | Gamma-secretase | Gamma-secretase C-terminal fragment 50 | Gamma-secretase C-terminal fragment 57 | Gamma-secretase C-terminal fragment 59 | P3(40) | P3(42) | PN-II | PreA4 | Protease nexin-II | S-APP-alpha | S-APP-beta | Soluble APP-alpha | Soluble APP-beta | beta-Amyloid Precursor Protein (APP) | ||
| Type: | Single-pass type I membrane protein | ||
| Mol. Mass.: | 86890.41 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | P05067 | ||
| Residue: | 770 | ||
| Sequence: |
| ||
| BDBM50595332 | |||
| n/a | |||
| Name | BDBM50595332 | ||
| Synonyms: | CHEMBL5179584 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C14H10O10 | ||
| Mol. Mass. | 338.2232 | ||
| SMILES | OC(=O)c1cc(O)c(O)c(O)c1-c1c(O)c(O)c(O)cc1C(O)=O |(2.01,.76,;2.01,-.78,;3.34,-1.55,;.67,-1.55,;.68,-3.09,;-.66,-3.86,;-.66,-5.4,;-2,-3.1,;-3.33,-3.87,;-1.99,-1.55,;-3.33,-.79,;-.66,-.78,;-.66,.76,;-2.01,1.52,;-3.34,.75,;-2.01,3.08,;-3.34,3.85,;-.67,3.85,;-.67,5.4,;.67,3.08,;.67,1.53,;2.16,1.93,;3.24,.84,;2.55,3.42,)| | ||
| Structure | 
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