| Reaction Details |
|---|
 | Report a problem with these data |
| Target | C-X-C chemokine receptor type 3 |
|---|
| Ligand | BDBM208550 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_2216804 (CHEMBL5129936) |
|---|
| IC50 | 5.9±n/a nM |
|---|
| Citation |  Meyer, EA; Äänismaa, P; Froidevaux, S; Keller, M; Piali, L; Caroff, E Discovery and J Med Chem65:11513-11532 (2022) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| C-X-C chemokine receptor type 3 |
|---|
| Name: | C-X-C chemokine receptor type 3 |
|---|
| Synonyms: | AAO92295.1 | C-X-C chemokine receptor type 3 | C-X-C chemokine receptor type 3 (CXCR3) | C-X-C chemokine receptor type 3 (CXCR3A) | CXCR3 | CXCR3A | CXCR3_HUMAN | GPR9 | chemokine (C-X-C motif) receptor 3 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 40665.65 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 368 |
|---|
| Sequence: | MVLEVSDHQVLNDAEVAALLENFSSSYDYGENESDSCCTSPPCPQDFSLNFDRAFLPALY
SLLFLLGLLGNGAVAAVLLSRRTALSSTDTFLLHLAVADTLLVLTLPLWAVDAAVQWVFG
SGLCKVAGALFNINFYAGALLLACISFDRYLNIVHATQLYRRGPPARVTLTCLAVWGLCL
LFALPDFIFLSAHHDERLNATHCQYNFPQVGRTALRVLQLVAGFLLPLLVMAYCYAHILA
VLLVSRGQRRLRAMRLVVVVVVAFALCWTPYHLVVLVDILMDLGALARNCGRESRVDVAK
SVTSGLGYMHCCLNPLLYAFVGVKFRERMWMLLLRLGCPNQRGLQRQPSSSRRDSSWSET
SEASYSGL
|
|
|
|---|
| BDBM208550 |
|---|
| n/a |
|---|
| Name | BDBM208550 |
|---|
| Synonyms: | US9266876, 17 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H22N8OS |
|---|
| Mol. Mass. | 458.539 |
|---|
| SMILES | C[C@@H]1CN(CCN1C(=O)Cn1cnc2cccnc12)c1scnc1-c1nc2ccccc2[nH]1 |
|---|
| Structure | 
|
|---|
Search and Browse
