Reaction Details |
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Target | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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Ligand | BDBM50170730 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_302233 (CHEMBL827006) |
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Kd | 5000±n/a nM |
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Citation | Smet, C; Duckert, JF; Wieruszeski, JM; Landrieu, I; Buée, L; Lippens, G; Déprez, B Control of protein-protein interactions: structure-based discovery of low molecular weight inhibitors of the interactions between Pin1 WW domain and phosphopeptides. J Med Chem48:4815-23 (2005) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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Name: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
Synonyms: | PIN1 | PIN1_HUMAN | PPIase Pin1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
Type: | PROTEIN |
Mol. Mass.: | 18248.11 |
Organism: | Homo sapiens (Human) |
Description: | ChEMBL_1502595 |
Residue: | 163 |
Sequence: | MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHL
LVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARG
DLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
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BDBM50170730 |
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n/a |
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Name | BDBM50170730 |
Synonyms: | CHEMBL371852 | Phosphoric acid mono-[(1R,2S)-2-[4,4-bis-(4-hydroxy-phenyl)-pentanoylamino]-3-((S)-2-carbamoyl-2,5-dihydro-pyrrol-1-yl)-1-methyl-3-oxo-propyl] ester |
Type | Small organic molecule |
Emp. Form. | C26H32N3O9P |
Mol. Mass. | 561.5207 |
SMILES | C[C@@H](OP(O)(O)=O)[C@H](NC(=O)CCC(C)(c1ccc(O)cc1)c1ccc(O)cc1)C(=O)N1CC=C[C@H]1C(N)=O |c:35| |
Structure |
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