| Reaction Details |
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 | Report a problem with these data |
| Target | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Ligand | BDBM50170732 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_302233 (CHEMBL827006) |
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| Kd | 910000±n/a nM |
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| Citation |  Smet, C; Duckert, JF; Wieruszeski, JM; Landrieu, I; Buée, L; Lippens, G; Déprez, B Control of protein-protein interactions: structure-based discovery of low molecular weight inhibitors of the interactions between Pin1 WW domain and phosphopeptides. J Med Chem48:4815-23 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Name: | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Synonyms: | PIN1 | PIN1_HUMAN | PPIase Pin1 | Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 18248.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1502595 |
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| Residue: | 163 |
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| Sequence: | MADEEKLPPGWEKRMSRSSGRVYYFNHITNASQWERPSGNSSSGGKNGQGEPARVRCSHL
LVKHSQSRRPSSWRQEKITRTKEEALELINGYIQKIKSGEEDFESLASQFSDCSSAKARG
DLGAFSRGQMQKPFEDASFALRTGEMSGPVFTDSGIHIILRTE
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| BDBM50170732 |
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| n/a |
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| Name | BDBM50170732 |
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| Synonyms: | CHEMBL191037 | [1-((S)-2-Carbamoyl-pyrrolidine-1-carbonyl)-4-((S)-2-hydroxy-3,4-dioxo-cyclobut-1-enylamino)-butyl]-carbamic acid 9H-fluoren-9-ylmethyl ester |
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| Type | Small organic molecule |
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| Emp. Form. | C29H30N4O7 |
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| Mol. Mass. | 546.5711 |
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| SMILES | NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNc1c(O)c(=O)c1=O)NC(=O)OCC1c2ccccc2-c2ccccc12 |
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| Structure | 
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