| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM50170821 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_303121 (CHEMBL829630) |
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| Ki | 4470.0±n/a nM |
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| Citation |  Perreira, M; Jiang, JK; Klutz, AM; Gao, ZG; Shainberg, A; Lu, C; Thomas, CJ; Jacobson, KA "Reversine" and its 2-substituted adenine derivatives as potent and selective A3 adenosine receptor antagonists. J Med Chem48:4910-8 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36520.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30542 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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| BDBM50170821 |
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| n/a |
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| Name | BDBM50170821 |
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| Synonyms: | CHEMBL365026 | N*6*-Cyclooctyl-N*2*-phenyl-9H-purine-2,6-diamine |
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| Type | Small organic molecule |
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| Emp. Form. | C19H24N6 |
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| Mol. Mass. | 336.4341 |
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| SMILES | C1CCCC(CCC1)Nc1nc(Nc2ccccc2)nc2nc[nH]c12 |
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| Structure | 
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