| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A2a |
|---|
| Ligand | BDBM50170831 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_303486 (CHEMBL838860) |
|---|
| Ki | >10000±n/a nM |
|---|
| Citation |  Perreira, M; Jiang, JK; Klutz, AM; Gao, ZG; Shainberg, A; Lu, C; Thomas, CJ; Jacobson, KA "Reversine" and its 2-substituted adenine derivatives as potent and selective A3 adenosine receptor antagonists. J Med Chem48:4910-8 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A2a |
|---|
| Name: | Adenosine receptor A2a |
|---|
| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 44716.46 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P29274 |
|---|
| Residue: | 412 |
|---|
| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
|
|
|
|---|
| BDBM50170831 |
|---|
| n/a |
|---|
| Name | BDBM50170831 |
|---|
| Synonyms: | CHEMBL188343 | N*6*-Cyclohexyl-N*2*-(4-morpholin-4-yl-phenyl)-9H-purine-2,6-diamine | N6-cyclohexyl-N2-(4-morpholinophenyl)-9H-purine-2,6-diamine | N~6~-cyclohexyl-N~2~-(4-morpholin-4-ylphenyl)-9H-purine-2,6-diamine |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H27N7O |
|---|
| Mol. Mass. | 393.4854 |
|---|
| SMILES | C1CCC(CC1)Nc1nc(Nc2ccc(cc2)N2CCOCC2)nc2nc[nH]c12 |
|---|
| Structure | 
|
|---|
Search and Browse
