| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A2b |
|---|
| Ligand | BDBM50170945 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_306686 (CHEMBL830020) |
|---|
| IC50 | >1000±n/a nM |
|---|
| Citation |  Baraldi, PG; Tabrizi, MA; Preti, D; Bovero, A; Fruttarolo, F; Romagnoli, R; Zaid, NA; Moorman, AR; Varani, K; Borea, PA New 2-arylpyrazolo[4,3-c]quinoline derivatives as potent and selective human A3 adenosine receptor antagonists. J Med Chem48:5001-8 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A2b |
|---|
| Name: | Adenosine receptor A2b |
|---|
| Synonyms: | AA2BR_HUMAN | ADENOSINE A2B | ADORA2B | Adenosine receptor A2B (A2B) | Adenosine receptors A2b | Adenosine receptors; A2a & A2b |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 36341.22 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | n/a |
|---|
| Residue: | 332 |
|---|
| Sequence: | MLLETQDALYVALELVIAALSVAGNVLVCAAVGTANTLQTPTNYFLVSLAAADVAVGLFA
IPFAITISLGFCTDFYGCLFLACFVLVLTQSSIFSLLAVAVDRYLAICVPLRYKSLVTGT
RARGVIAVLWVLAFGIGLTPFLGWNSKDSATNNCTEPWDGTTNESCCLVKCLFENVVPMS
YMVYFNFFGCVLPPLLIMLVIYIKIFLVACRQLQRTELMDHSRTTLQREIHAAKSLAMIV
GIFALCWLPVHAVNCVTLFQPAQGKNKPKWAMNMAILLSHANSVVNPIVYAYRNRDFRYT
FHKIISRYLLCQADVKSGNGQAGVQPALGVGL
|
|
|
|---|
| BDBM50170945 |
|---|
| n/a |
|---|
| Name | BDBM50170945 |
|---|
| Synonyms: | 2-(4-Ethyl-phenyl)-2,5-dihydro-pyrazolo[4,3-c]quinolin-4-one | CHEMBL188436 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H15N3O |
|---|
| Mol. Mass. | 289.3312 |
|---|
| SMILES | CCc1ccc(cc1)-n1cc2c(n1)c1ccccc1[nH]c2=O |
|---|
| Structure | 
|
|---|
Search and Browse
