| Reaction Details |
|---|
 | Report a problem with these data |
| Target | D(2) dopamine receptor |
|---|
| Ligand | BDBM50171885 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_303800 (CHEMBL829849) |
|---|
| Ki | 670±n/a nM |
|---|
| Citation |  Fiorino, F; Perissutti, E; Severino, B; Santagada, V; Cirillo, D; Terracciano, S; Massarelli, P; Bruni, G; Collavoli, E; Renner, C; Caliendo, G New 5-hydroxytryptamine(1A) receptor ligands containing a norbornene nucleus: synthesis and in vitro pharmacological evaluation. J Med Chem48:5495-503 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| D(2) dopamine receptor |
|---|
| Name: | D(2) dopamine receptor |
|---|
| Synonyms: | DOPAMINE D2 | DOPAMINE D2 Long | DOPAMINE D2 Short | DRD2_RAT | Dopamine D2 receptor | Dopamine2-like | Drd2 |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 50931.60 |
|---|
| Organism: | Rattus norvegicus (rat) |
|---|
| Description: | P61169 |
|---|
| Residue: | 444 |
|---|
| Sequence: | MDPLNLSWYDDDLERQNWSRPFNGSEGKADRPHYNYYAMLLTLLIFIIVFGNVLVCMAVS
REKALQTTTNYLIVSLAVADLLVATLVMPWVVYLEVVGEWKFSRIHCDIFVTLDVMMCTA
SILNLCAISIDRYTAVAMPMLYNTRYSSKRRVTVMIAIVWVLSFTISCPLLFGLNNTDQN
ECIIANPAFVVYSSIVSFYVPFIVTLLVYIKIYIVLRKRRKRVNTKRSSRAFRANLKTPL
KGNCTHPEDMKLCTVIMKSNGSFPVNRRRMDAARRAQELEMEMLSSTSPPERTRYSPIPP
SHHQLTLPDPSHHGLHSNPDSPAKPEKNGHAKIVNPRIAKFFEIQTMPNGKTRTSLKTMS
RRKLSQQKEKKATQMLAIVLGVFIICWLPFFITHILNIHCDCNIPPVLYSAFTWLGYVNS
AVNPIIYTTFNIEFRKAFMKILHC
|
|
|
|---|
| BDBM50171885 |
|---|
| n/a |
|---|
| Name | BDBM50171885 |
|---|
| Synonyms: | 4-{3-[4-(3-Trifluoromethyl-phenyl)-piperazin-1-yl]-propoxy}-4-aza-tricyclo[5.2.1.0*2,6*]dec-8-ene-3,5-dione | CHEMBL191226 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C23H26F3N3O3 |
|---|
| Mol. Mass. | 449.466 |
|---|
| SMILES | FC(F)(F)c1cccc(c1)N1CCN(CCCON2C(=O)C3C4CC(C=C4)C3C2=O)CC1 |c:26| |
|---|
| Structure | 
|
|---|
Search and Browse
