| Reaction Details |
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 | Report a problem with these data |
| Target | D(3) dopamine receptor |
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| Ligand | BDBM50596936 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_2222521 (CHEMBL5135855) |
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| Ki | 1246±n/a nM |
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| Citation |  Orr, MJ; Cao, AB; Wang, CT; Gaisin, A; Csakai, A; Friswold, AP; Meltzer, HY; McCorvy, JD; Scheidt, KA Discovery of Highly Potent Serotonin 5-HT ACS Med Chem Lett13:648-657 (2022) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| D(3) dopamine receptor |
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| Name: | D(3) dopamine receptor |
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| Synonyms: | DRD3 | DRD3_HUMAN | Dopamine D3 receptor |
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| Type: | PROTEIN |
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| Mol. Mass.: | 44213.40 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_105671 |
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| Residue: | 400 |
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| Sequence: | MASLSQLSGHLNYTCGAENSTGASQARPHAYYALSYCALILAIVFGNGLVCMAVLKERAL
QTTTNYLVVSLAVADLLVATLVMPWVVYLEVTGGVWNFSRICCDVFVTLDVMMCTASILN
LCAISIDRYTAVVMPVHYQHGTGQSSCRRVALMITAVWVLAFAVSCPLLFGFNTTGDPTV
CSISNPDFVIYSSVVSFYLPFGVTVLVYARIYVVLKQRRRKRILTRQNSQCNSVRPGFPQ
QTLSPDPAHLELKRYYSICQDTALGGPGFQERGGELKREEKTRNSLSPTIAPKLSLEVRK
LSNGRLSTSLKLGPLQPRGVPLREKKATQMVAIVLGAFIVCWLPFFLTHVLNTHCQTCHV
SPELYSATTWLGYVNSALNPVIYTTFNIEFRKAFLKILSC
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| BDBM50596936 |
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| n/a |
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| Name | BDBM50596936 |
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| Synonyms: | CHEMBL5170784 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H17ClN2O2 |
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| Mol. Mass. | 328.793 |
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| SMILES | COc1ccc(C2NCCc3c2[nH]c2ccc(Cl)cc32)c(O)c1 |
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| Structure | 
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