| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Alpha-1D adrenergic receptor |
|---|
| Ligand | BDBM31046 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_320870 (CHEMBL884795) |
|---|
| Ki | 19±n/a nM |
|---|
| Citation |  Hong, SS; Bavadekar, SA; Lee, SI; Patil, PN; Lalchandani, SG; Feller, DR; Miller, DD Bioisosteric phentolamine analogs as potent alpha-adrenergic antagonists. Bioorg Med Chem Lett15:4691-5 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Alpha-1D adrenergic receptor |
|---|
| Name: | Alpha-1D adrenergic receptor |
|---|
| Synonyms: | ADA1D_HUMAN | ADRA1A | ADRA1D | Adrenergic receptor | Adrenergic receptor alpha | Alpha 1D-adrenoceptor | Alpha 1D-adrenoreceptor | Alpha adrenergic receptor (1a and 1d) | Alpha-1D adrenoceptor | Alpha-adrenergic receptor 1a | adrenergic Alpha1D |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 60485.82 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | adrenergic Alpha1D ADRA1D HUMAN::P25100 |
|---|
| Residue: | 572 |
|---|
| Sequence: | MTFRDLLSVSFEGPRPDSSAGGSSAGGGGGSAGGAAPSEGPAVGGVPGGAGGGGGVVGAG
SGEDNRSSAGEPGSAGAGGDVNGTAAVGGLVVSAQGVGVGVFLAAFILMAVAGNLLVILS
VACNRHLQTVTNYFIVNLAVADLLLSATVLPFSATMEVLGFWAFGRAFCDVWAAVDVLCC
TASILSLCTISVDRYVGVRHSLKYPAIMTERKAAAILALLWVVALVVSVGPLLGWKEPVP
PDERFCGITEEAGYAVFSSVCSFYLPMAVIVVMYCRVYVVARSTTRSLEAGVKRERGKAS
EVVLRIHCRGAATGADGAHGMRSAKGHTFRSSLSVRLLKFSREKKAAKTLAIVVGVFVLC
WFPFFFVLPLGSLFPQLKPSEGVFKVIFWLGYFNSCVNPLIYPCSSREFKRAFLRLLRCQ
CRRRRRRRPLWRVYGHHWRASTSGLRQDCAPSSGDAPPGAPLALTALPDPDPEPPGTPEM
QAPVASRRKPPSAFREWRLLGPFRRPTTQLRAKVSSLSHKIRAGGAQRAEAACAQRSEVE
AVSLGVPHEVAEGATCQAYELADYSNLRETDI
|
|
|
|---|
| BDBM31046 |
|---|
| n/a |
|---|
| Name | BDBM31046 |
|---|
| Synonyms: | 3-[4,5-dihydro-1H-imidazol-2-ylmethyl-(4-methylphenyl)amino]phenol;methanesulfonic acid | 3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;hydrochloride | 3-[N-(2-imidazolin-2-ylmethyl)-4-methyl-anilino]phenol;mesylic acid | 3-[N-(4,5-dihydro-1H-imidazol-2-ylmethyl)-4-methylanilino]phenol;methanesulfonic acid | MLS000069487 | PHENTOLAMINE | PHENTOLAMINE MESYLATE | SMR000059054 | cid_5775 | cid_91430 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C17H19N3O |
|---|
| Mol. Mass. | 281.3523 |
|---|
| SMILES | Cc1ccc(cc1)N(CC1=NCCN1)c1cccc(O)c1 |t:10| |
|---|
| Structure | 
|
|---|
Search and Browse
