| Reaction Details |
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 | Report a problem with these data |
| Target | Integrase |
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| Ligand | BDBM50174222 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_321235 (CHEMBL881770) |
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| IC50 | 1000±n/a nM |
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| Citation |  Bailly, F; Queffelec, C; Mbemba, G; Mouscadet, JF; Cotelle, P Synthesis and HIV-1 integrase inhibitory activities of caffeic acid dimers derived from Salvia officinalis. Bioorg Med Chem Lett15:5053-6 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrase |
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| Name: | Integrase |
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| Synonyms: | Human immunodeficiency virus type 1 integrase |
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| Type: | PROTEIN |
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| Mol. Mass.: | 32231.48 |
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| Organism: | Human immunodeficiency virus 1 |
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| Description: | ChEMBL_90865 |
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| Residue: | 288 |
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| Sequence: | FLDGIDKAQDEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTIHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVVESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPLWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKVKIIRDYGKQMAGDDCVASRQDED
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| BDBM50174222 |
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| n/a |
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| Name | BDBM50174222 |
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| Synonyms: | 3-[3-(6,7-Dihydroxy-2-oxo-2H-chromen-3-yloxy)-4-hydroxy-phenyl]-acrylic acid | CHEMBL196272 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H12O8 |
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| Mol. Mass. | 356.2831 |
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| SMILES | OC(=O)\C=C\c1ccc(O)c(Oc2cc3cc(O)c(O)cc3oc2=O)c1 |
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| Structure | 
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