Reaction Details |
| Report a problem with these data |
Target | 5-hydroxytryptamine receptor 6 |
---|
Ligand | BDBM50174272 |
---|
Substrate/Competitor | n/a |
---|
Meas. Tech. | ChEMBL_326768 (CHEMBL860114) |
---|
Ki | 21±n/a nM |
---|
Citation | Pullagurla, M; Siripurapu, U; Kolanos, R; Bondarev, ML; Dukat, M; Setola, V; Roth, BL; Glennon, RA Binding of amine-substituted N1-benzenesulfonylindoles at human 5-HT6 serotonin receptors. Bioorg Med Chem Lett15:5298-302 (2005) [PubMed] Article |
---|
More Info.: | Get all data from this article, Assay Method |
---|
|
5-hydroxytryptamine receptor 6 |
---|
Name: | 5-hydroxytryptamine receptor 6 |
Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
Type: | G Protein-Coupled Receptor (GPCR) |
Mol. Mass.: | 46968.43 |
Organism: | Homo sapiens (Human) |
Description: | P50406 |
Residue: | 440 |
Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
|
|
|
BDBM50174272 |
---|
n/a |
---|
Name | BDBM50174272 |
Synonyms: | 1-(4-aminophenylsulfonyl)-N-methyl-1H-indol-4-amine | CHEMBL381415 |
Type | Small organic molecule |
Emp. Form. | C15H15N3O2S |
Mol. Mass. | 301.364 |
SMILES | CNc1cccc2n(ccc12)S(=O)(=O)c1ccc(N)cc1 |
Structure |
|