| Reaction Details |
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 | Report a problem with these data |
| Target | Leukotriene B4 receptor 1 |
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| Ligand | BDBM50174608 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_321566 (CHEMBL882595) |
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| pH | 7.2±n/a |
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| IC50 | 16±n/a nM |
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| Comments | extracted |
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| Citation |  Broekema, M; van Eerd, JJ; Oyen, WJ; Corstens, FH; Liskamp, RM; Boerman, OC; Harris, TD Synthesis of leukotriene B4 antagonists labeled with In-111 or Tc-99m to image infectious and inflammatory foci. J Med Chem48:6442-53 (2005) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Leukotriene B4 receptor 1 |
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| Name: | Leukotriene B4 receptor 1 |
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| Synonyms: | BLT | BLT1 | BLTR | CMKRL1 | Chemoattractant receptor-like 1 | G-protein coupled receptor 16 | GPR16 | LT4R1_HUMAN | LTB4-R 1 | LTB4R | Leukotriene B4 R1 | Leukotriene B4 receptor | Leukotriene B4 receptor 1 | P2RY7 | P2Y purinoceptor 7 | P2Y7 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 37582.68 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q15722 |
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| Residue: | 352 |
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| Sequence: | MNTTSSAAPPSLGVEFISLLAIILLSVALAVGLPGNSFVVWSILKRMQKRSVTALMVLNL
ALADLAVLLTAPFFLHFLAQGTWSFGLAGCRLCHYVCGVSMYASVLLITAMSLDRSLAVA
RPFVSQKLRTKAMARRVLAGIWVLSFLLATPVLAYRTVVPWKTNMSLCFPRYPSEGHRAF
HLIFEAVTGFLLPFLAVVASYSDIGRRLQARRFRRSRRTGRLVVLIILTFAAFWLPYHVV
NLAEAGRALAGQAAGLGLVGKRLSLARNVLIALAFLSSSVNPVLYACAGGGLLRSAGVGF
VAKLLEGTGSEASSTRRGGSLGQTARSGPAALEPGPSESLTASSPLKLNELN
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| BDBM50174608 |
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| n/a |
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| Name | BDBM50174608 |
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| Synonyms: | CHEMBL406432 | HYNIC Conjugate |
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| Type | Small organic molecule |
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| Emp. Form. | C65H86N14O22S4 |
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| Mol. Mass. | 1543.719 |
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| SMILES | CC(C)(CCCCOc1cc(cc(n1)-c1ccccc1)-c1ccccc1)c1nnnn1CCCCC(=O)NCCCOCCOCCOCCCNC(=O)[C@H](CS(O)(=O)=O)NC(=O)[C@H](CS(O)(=O)=O)NC(=O)[C@H](CS(O)(=O)=O)NC(=O)[C@H](CS(O)(=O)=O)NC(=O)c1ccc(N=NCc2ccccc2)nc1 |w:95.99| |
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| Structure | 
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