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TargetCarbonic anhydrase 2
LigandBDBM50175051
Substrate/Competitorn/a
Meas. Tech.ChEMBL_326924 (CHEMBL854316)
Ki 9.1±n/a nM
Citation Poulsen, SABornaghi, LFHealy, PC Synthesis and structure-activity relationships of novel benzene sulfonamides with potent binding affinity for bovine carbonic anhydrase II. Bioorg Med Chem Lett15:5429-33 (2005) [PubMed]  Article
More Info.:Get all data from this article,  Assay Method
 
Carbonic anhydrase 2
Name:Carbonic anhydrase 2
Synonyms:CA2 | CAH2_BOVIN | Carbonic anhydrase | Carbonic anhydrase 2 | Carbonic anhydrase II | Carbonic anhydrase II (CA II) | Carbonic anhydrase II (CA-II)
Type:Enzyme Catalytic Domain
Mol. Mass.:29115.93
Organism:Bos taurus
Description:n/a
Residue:260
Sequence:
MSHHWGYGKHNGPEHWHKDFPIANGERQSPVDIDTKAVVQDPALKPLALVYGEATSRRMV
NNGHSFNVEYDDSQDKAVLKDGPLTGTYRLVQFHFHWGSSDDQGSEHTVDRKKYAAELHL
VHWNTKYGDFGTAAQQPDGLAVVGVFLKVGDANPALQKVLDALDSIKTKGKSTDFPNFDP
GSLLPNVLDYWTYPGSLTTPPLLESVTWIVLKEPISVSSQQMLKFRTLNFNAEGEPELLM
LANWRPAQPLKNRQVRGFPK
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BDBM50175051
n/a
NameBDBM50175051
Synonyms:(2Z)-4-hydroxybut-2-enyl-4-(aminosulfonyl)benzoate | CHEMBL199368
TypeSmall organic molecule
Emp. Form.C11H13NO5S
Mol. Mass.271.29
SMILESNS(=O)(=O)c1ccc(cc1)C(=O)OC\C=C/CO
Structure
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